Synucleinopathies are neurodegenerative disorders characterized by alpha-synuclein
(αSyn) accumulation in neurons or glial cells, including Parkinson's disease (PD), dementia …

Neurotransmitters are considered as a fundamental regulator in the process of neuronal
growth, differentiation and survival. Parkinson's Disease (PD) occurs due to extensive …

Besides the hallmark motor symptoms (rest tremor, hypokinesia, rigidity, and postural
instability), patients with Parkinson's disease (PD) have non-motor symptoms, namely …

A study on the anxiolytic activity of the new derivatives of 11-dialkylaminoethyl-2, 3, 4, 5-
tetrahydrodiazepino [1, 2-a] benzimidazole, containing privileged scaffolds of …

Background The treatment options for cognitive impairments in Parkinson's disease (PD) are
limited. Repetitive transcranial magnetic stimulation has been applied in various …

Pharmacoresistant temporal lobe epilepsy affects millions of people around the world with
uncontrolled seizures and comorbidities, like anxiety, being the most problematic aspects …

Background: Parkinson's disease (PD) is commonly accompanied with anxiety disorder,
however, the mechanisms underlying PD-mediated anxiety remain elusive. The lateral …

Parkinson disease (PD) is a progressive neurodegenerative disorder that is often
accompanied by motor and psychiatric symptoms. Various approaches have been proposed …

Affective neuropsychiatric disorders such as depression, anxiety and apathy are among the
most frequent non-motor symptoms observed in people with Parkinson's disease (PD) …

Degradation products of the essential amino acid tryptophan (Trp) are important signaling
molecules in the mammalian brain. Trp is metabolized either through the kynurenine …