Renal drug transporters and drug interactions

A Ivanyuk, F Livio, J Biollaz, T Buclin - Clinical pharmacokinetics, 2017 - Springer
Transporters in proximal renal tubules contribute to the disposition of numerous drugs.
Furthermore, the molecular mechanisms of tubular secretion have been progressively …

The 6R's of drug induced nephrotoxicity

L Awdishu, RL Mehta - BMC nephrology, 2017 - Springer
Drug induced kidney injury is a frequent adverse event which contributes to morbidity and
increased healthcare utilization. Our current knowledge of drug induced kidney disease is …

[图书][B] Guidelines for the prevention care and treatment of persons with chronic hepatitis B infection: Mar-15

World Health Organization - 2015 - books.google.com
These are the first World Health Organization (WHO) guidelines for the prevention care and
treatment of persons living with CHB infection and complement similar recent published …

Phosphate homeostasis and disorders

P Manghat, R Sodi… - Annals of clinical …, 2014 - journals.sagepub.com
Recent studies of inherited disorders of phosphate metabolism have shed new light on the
understanding of phosphate metabolism. Phosphate has important functions in the body and …

Antiretrovirals and the kidney in current clinical practice: renal pharmacokinetics, alterations of renal function and renal toxicity

JC Yombi, A Pozniak, M Boffito, R Jones, S Khoo… - Aids, 2014 - journals.lww.com
Assessment of renal function in HIV-positive patients is of increasing importance in the
context of ageing and associated comorbidities. Exposure to nephrotoxic medications is …

The role of ABCC10/MRP7 in anti-cancer drug resistance and beyond

DQ Chen, Y Xie, LQ Cao, JS Fleishman, Y Chen… - Drug Resistance …, 2024 - Elsevier
Abstract Multidrug resistance protein 7 (MRP7), also known as ATP-binding cassette (ABC)
transporter subfamily C10 (ABCC10), is an ABC transporter that was first identified in 2001 …

Tenofovir-induced nephrotoxicity: incidence, mechanism, risk factors, prognosis and proposed agents for prevention

A Jafari, H Khalili, S Dashti-Khavidaki - European journal of clinical …, 2014 - Springer
Objective In this study, data regarding epidemiology, risk factors, pathogenesis and outcome
of tenofovir-induced nephrotoxicity will be reviewed, and current and future approaches for …

The role of drug transporters in the kidney: lessons from tenofovir

DM Moss, M Neary, A Owen - Frontiers in pharmacology, 2014 - frontiersin.org
Tenofovir disoproxil fumarate, the prodrug of nucleotide reverse transcriptase inhibitor
tenofovir, shows high efficacy and relatively low toxicity in HIV patients. However, long-term …

Single Nucleotide Polymorphisms in ABCC2 Associate With Tenofovir-Induced Kidney Tubular Dysfunction in Japanese Patients With HIV-1 Infection: A …

T Nishijima, H Komatsu, K Higasa… - Clinical Infectious …, 2012 - academic.oup.com
Background. Tenofovir is a widely used antiretroviral drug although it can cause kidney
tubular dysfunction (KTD). The aim of this study was to determine the association between …

Renal function of participants in the Bangkok tenofovir study—Thailand, 2005–2012

M Martin, S Vanichseni, P Suntharasamai… - Clinical infectious …, 2014 - academic.oup.com
Renal Function of Participants in the Bangkok Tenofovir Study—Thailand, 2005–2012 | Clinical
Infectious Diseases | Oxford Academic Skip to Main Content Advertisement Oxford Academic …