In this brief review and perspective, we address the question of whether the immune
responses that bring about immune control of acute HIV infection are the same as, or distinct …

Individuals infected with HIV-1 require lifelong antiretroviral therapy, because interruption of
treatment leads to rapid rebound viraemia. Here we report on a phase 1b clinical trial in …

Among the top priorities of the HIV field is the search for therapeutic interventions that can
lead to sustained antiretroviral therapy (ART)-free HIV remission. Although the majority of …

HIV remission can be achieved in some people, called post-treatment HIV controllers, after
antiretroviral treatment discontinuation. Treatment initiation close to the time of infection was …

Plasma viral load (VL) and CD4+ T cell count are widely used as biomarkers of HIV type 1
(HIV-1) replication, pathogenesis, and response to antiretroviral therapy (ART). However …

TGF-β plays a critical role in maintaining immune cells in a resting state by inhibiting cell
activation and proliferation. Resting HIV-1 target cells represent the main cellular reservoir …

Abstract Purpose of Review The purpose of this review was to provide current data on
clinical presentation, diagnosis, and treatment of primary HIV infection (PHI). Recent …

In the search for control of human immunodeficiency virus type 1 (HIV-1) infection without
antiretroviral therapy, posttreatment controllers (PTCs) are models of HIV remission. To …

Background Electrocautery ablation (EA) is a common treatment modality for patients with
anal high‐grade squamous intraepithelial lesions (HSILs), but to the authors' knowledge its …

HIV-1 disrupts the host epigenetic landscape with consequences for disease pathogenesis,
viral persistence, and HIV-associated comorbidities. Here, we examined how soon after …