Metal drugs and the anticancer immune response

B Englinger, C Pirker, P Heffeter, A Terenzi… - Chemical …, 2018 - ACS Publications
The immune system deploys a multitude of innate and adaptive mechanisms not only to
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …

Engineering immunomodulatory biomaterials for type 1 diabetes

CL Stabler, Y Li, JM Stewart… - Nature Reviews Materials, 2019 - nature.com
A cure for type 1 diabetes (T1D) would help millions of people worldwide but remains
elusive to date. Tolerogenic vaccines and β-cell replacement therapy are complementary …

Modulation of immune‐inflammatory responses in abdominal aortic aneurysm: Emerging molecular targets

H Li, S Bai, Q Ao, X Wang, X Tian, X Li… - Journal of …, 2018 - Wiley Online Library
Abdominal aortic aneurysm (AAA), a deadly vascular disease in human, is a chronic
degenerative process of the abdominal aorta. In this process, inflammatory responses and …

Use of poly lactic-co-glycolic acid nano and micro particles in the delivery of drugs modulating different phases of inflammation

C Puricelli, CL Gigliotti, I Stoppa, S Sacchetti… - Pharmaceutics, 2023 - mdpi.com
Chronic inflammation contributes to the pathogenesis of many diseases, including
apparently unrelated conditions such as metabolic disorders, cardiovascular diseases …

Regulatory T lymphocytes in periodontitis: a translational view

C Alvarez, C Rojas, L Rojas, EA Cafferata… - Mediators of …, 2018 - Wiley Online Library
Periodontitis is a chronic immuno‐inflammatory disease in which the disruption of the
balance between host and microbiota interactions is key to the onset and progression of the …

PEGylation enables subcutaneously administered nanoparticles to induce antigen-specific immune tolerance

PY Li, F Bearoff, P Zhu, Z Fan, Y Zhu, M Fan… - Journal of controlled …, 2021 - Elsevier
The development of nanomaterials to induce antigen-specific immune tolerance has shown
promise for treating autoimmune diseases. While PEGylation has been widely used to …

Intermittent fasting modulates immune response by generating tregs via TGF-β Dependent mechanisms in obese mice with allergic contact dermatitis

SC Han, JI Kang, YK Choi, HJ Boo… - Biomolecules & …, 2023 - pmc.ncbi.nlm.nih.gov
People with obesity maintain low levels of inflammation; therefore, their exposure to foreign
antigens can trigger an excessive immune response. In people with obesity or allergic …

Cell and biomaterial delivery strategies to induce immune tolerance

BL Scotland, JR Shaw, S Dharmaraj, N Caprio… - Advanced Drug Delivery …, 2023 - Elsevier
The prevalence of immune-mediated disorders, including autoimmune conditions and
allergies, is steadily increasing. However, current therapeutic approaches are often non …

Engineering immune tolerance with biomaterials

JM Gammon, CM Jewell - Advanced healthcare materials, 2019 - Wiley Online Library
Autoimmune diseases, rejection of transplanted organs and grafts, chronic inflammatory
diseases, and immune‐mediated rejection of biologic drugs impact a large number of …

Pathomechanisms of contact sensitization

PR Esser, SF Martin - Current allergy and asthma reports, 2017 - Springer
Contact sensitization is the initial process involved in the development of an allergic reaction
to xenobiotic environmental substances. Here, we briefly describe the differences between …