The mechanical properties of bone are fundamental to the ability of our skeletons to support
movement and to provide protection to our vital organs. As such, deterioration in mechanical …

In this paper, we review analytical and computational models of bone fracture and strength.
Bone fracture is a complex phenomenon due to the composite, inhomogeneous and …

MicroComputed Tomography has become the gold standard for studying 3D microscopic
structures nondestructively, and this book provides up-to-date coverage of the modality. The …

Increases in cortical porosity (Ct. Po) and decreases in cortical thickness (Ct. Th) are
associated with increased bone fragility. The purpose of this study was to validate an …

Numerous clinical cohorts are exposed to reduced skeletal loading and associated bone
loss, including surgical patients, stroke and spinal cord injury victims, and women on bed …

The risk of fracture increases with age due to the decline of bone mass and bone quality.
One of the age-related changes in bone quality occurs through the formation and …

The purpose of this study was to develop a finite element model based on continuum
damage mechanics in order to simulate the profile of the fractured area of proximal femur …

Bone is a hierarchical material that exhibit fracture mechanisms at multiple scales and will
benefit from a multiscale evaluation approach for better fracture risk assessment. This study …

Bone strength is dependent on bone density and microstructure. High-resolution peripheral
quantitative computed tomography (HR-pQCT) can measure microstructure but is somewhat …

Abstract Purpose of Review The goal of this review is to summarize recent advances in
modeling of bone fracture using fracture mechanics–based approaches at multiple length …