The elegant mechanisms by which naturally occurring selfish genetic elements, such as
transposable elements, meiotic drive genes, homing endonuclease genes and Wolbachia …

Mosquitoes containing gene drive systems are being developed as complementary tools to
prevent transmission of malaria and other mosquito-borne diseases. As with any new tool …

Effective vector control, and more specifically mosquito control, is a complex and difficult
problem, as illustrated by the continuing prevalence (and spread) of mosquito-transmitted …

Background Reduction or elimination of vector populations will tend to reduce or eliminate
transmission of vector-borne diseases. One potential method for environmentally-friendly …

Background Dengue is the most important mosquito-borne viral disease. In the absence of
specific drugs or vaccines, control focuses on suppressing the principal mosquito vector …

We have developed genetically modified Ae. aegypti mosquitoes that activate the conserved
antiviral JAK/STAT pathway in the fat body tissue, by overexpressing either the receptor …

A causative agent of human malaria, Plasmodium falciparum, is transmitted by Anopheles
mosquitoes. The malaria parasite is under intensive attack from the mosquito's innate …

Population replacement strategies for controlling transmission of mosquito-borne diseases
call for the introgression of antipathogen effector genes into vector populations. It is …

The generation of transgenic mosquitoes with a minimal fitness load is a prerequisite for the
success of strategies for controlling mosquito-borne diseases using transgenic insects. It is …

Malaria is one of the deadliest diseases. Because of the ineffectiveness of current malaria-
control methods, several novel mosquito vector-based control strategies have been …