Neutrophils are the frontline cells in response to microbial infections and are involved in a
range of inflammatory disorders in the body. In recent years, neutrophils have gained …

Hypoxia is an integral component of the tumor microenvironment. Either as chronic or
cycling hypoxia, it exerts a similar effect on cancer processes by activating hypoxia-inducible …

Background Deciphering intra‐and inter‐tumoural heterogeneity is essential for
understanding the biology of gastric cancer (GC) and its metastasis and identifying effective …

The advent of immunotherapy has made an indelible mark on the field of cancer therapy,
especially the application of immune checkpoint inhibitors in clinical practice. Although …

Transforming growth factor-β (TGF-β) signaling shows important roles in both physiology
and pathology, especially in the progression of inflammatory diseases including cancer …

Zebrafish are teleosts (bony fish) that share with mammals a common ancestor belonging to
the phylum Osteichthyes, from which their endoskeletal systems have been inherited …

Zebrafish (Danio rerio) is a valuable non-mammalian vertebrate model widely used to study
development and disease, including more recently cancer. The evolutionary conservation of …

Tumors are dynamic tissue masses, so requiring continuous exposure to the host cells,
nurturing them into pave a path for tumor growth and metastasis. CXC chemokine ligand 12 …

Acute lung injury (ALI), a critical respiratory disorder that causes diffuse alveolar injury leads
to high mortality rates with no effective treatment. ALI is characterized by varying degrees of …

Simple Summary Tumor angiogenesis is one of the most critical steps in the progression of
cancer. Owing to its fundamental role in tumor growth and metastasis, tumor angiogenesis is …