[HTML][HTML] Global colorectal cancer burden in 2020 and projections to 2040
As the third most common malignancy and the second most deadly cancer, colorectal
cancer (CRC) induces estimated 1.9 million incidence cases and 0.9 million deaths …
cancer (CRC) induces estimated 1.9 million incidence cases and 0.9 million deaths …
Precision oncology in metastatic colorectal cancer—from biology to medicine
Remarkable progress has been made in the development of biomarker-driven targeted
therapies for patients with multiple cancer types, including melanoma, breast and lung …
therapies for patients with multiple cancer types, including melanoma, breast and lung …
[HTML][HTML] Deep learning based tissue analysis predicts outcome in colorectal cancer
Image-based machine learning and deep learning in particular has recently shown expert-
level accuracy in medical image classification. In this study, we combine convolutional and …
level accuracy in medical image classification. In this study, we combine convolutional and …
The consensus molecular subtypes of colorectal cancer
Colorectal cancer (CRC) is a frequently lethal disease with heterogeneous outcomes and
drug responses. To resolve inconsistencies among the reported gene expression–based …
drug responses. To resolve inconsistencies among the reported gene expression–based …
Biomarker-guided therapy for colorectal cancer: strength in complexity
A Sveen, S Kopetz, RA Lothe - Nature Reviews Clinical Oncology, 2020 - nature.com
The number of molecularly stratified treatment options available to patients with colorectal
cancer (CRC) is increasing, with a parallel rise in the use of biomarkers to guide …
cancer (CRC) is increasing, with a parallel rise in the use of biomarkers to guide …
The current state of molecular testing in the treatment of patients with solid tumors, 2019
The world of molecular profiling has undergone revolutionary changes over the last few
years as knowledge, technology, and even standard clinical practice have evolved. Broad …
years as knowledge, technology, and even standard clinical practice have evolved. Broad …
[HTML][HTML] Management of BRAF-mutant metastatic colorectal cancer: a review of treatment options and evidence-based guidelines
Background Colorectal cancer (CRC) is still a leading cause of cancer-related deaths in the
United States and worldwide, despite recent improvements in cancer management. CRC …
United States and worldwide, despite recent improvements in cancer management. CRC …
[HTML][HTML] Pathological features and prognostication in colorectal cancer
The prognostication of colorectal cancer (CRC) has traditionally relied on staging as defined
by the Union for International Cancer Control (UICC) and American Joint Committee on …
by the Union for International Cancer Control (UICC) and American Joint Committee on …
[HTML][HTML] Colorectal cancer: genetic abnormalities, tumor progression, tumor heterogeneity, clonal evolution and tumor-initiating cells
U Testa, E Pelosi, G Castelli - Medical Sciences, 2018 - mdpi.com
Colon cancer is the third most common cancer worldwide. Most colorectal cancer
occurrences are sporadic, not related to genetic predisposition or family history; however, 20 …
occurrences are sporadic, not related to genetic predisposition or family history; however, 20 …
Adjuvant Fluorouracil, Leucovorin, and Oxaliplatin in Stage II to III Colon Cancer: Updated 10-Year Survival and Outcomes According to BRAF Mutation and Mismatch …
T André, A De Gramont, D Vernerey… - Journal of Clinical …, 2015 - ascopubs.org
Purpose The MOSAIC (Multicenter International Study of Oxaliplatin/Fluorouracil/Leucovorin
in the Adjuvant Treatment of Colon Cancer) study has demonstrated 3-year disease-free …
in the Adjuvant Treatment of Colon Cancer) study has demonstrated 3-year disease-free …