Abstract The original Human Connectome Project yielded a rich data set on structural and
functional connectivity in a large sample of healthy young adults using improved methods of …

Focusing primarily on functional magnetic resonance imaging (fMRI), this article reviews
evidence regarding the roles of subregions of the medial temporal lobes, prefrontal cortex …

Elevated hippocampal activation is observed in conditions that confer risk for Alzheimer's
disease, including amnestic mild cognitive impairment (aMCI). Studies in relevant animal …

The fine spatial scales of the structures in the human brain represent an enormous
challenge to the successful integration of information from different images for both within …

Abstract Changes in memory performance are one of the hallmark symptoms of mild
cognitive impairment and are affected by healthy aging as well. Pattern separation, which …

Pattern separation, the process of transforming similar representations or memories into
highly dissimilar, nonoverlapping representations, is a key component of many functions …

There is widespread evidence that memory deteriorates with aging, however the exact
mechanisms that underlie these changes are not well understood. Given the growing size of …

Objective An increasing number of human in vivo magnetic resonance imaging (MRI)
studies have focused on examining the structure and function of the subfields of the …

Studies of individuals with amnestic mild cognitive impairment (aMCI) have detected
hyperactivity in the hippocampus during task-related functional magnetic resonance imaging …

Functional magnetic resonance imaging (fMRI) studies have observed hyperactivity in the
hippocampal region in individuals with Mild Cognitive Impairment (MCI). However, the …