The pathophysiology of 'happy'hypoxemia in COVID-19

S Dhont, E Derom, E Van Braeckel, P Depuydt… - Respiratory …, 2020 - Springer
The novel coronavirus disease 2019 (COVID-19) pandemic is a global crisis, challenging
healthcare systems worldwide. Many patients present with a remarkable disconnect in rest …

Respiratory drive in the acute respiratory distress syndrome: pathophysiology, monitoring, and therapeutic interventions

E Spinelli, T Mauri, JR Beitler, A Pesenti… - Intensive care medicine, 2020 - Springer
Neural respiratory drive, ie, the activity of respiratory centres controlling breathing, is an
overlooked physiologic variable which affects the pathophysiology and the clinical outcome …

Respiratory drive in critically ill patients. Pathophysiology and clinical implications

K Vaporidi, E Akoumianaki, I Telias… - American journal of …, 2020 - atsjournals.org
Respiratory drive, the intensity of the respiratory center's output, determines the effort
exerted in each breath. The increasing awareness of the adverse effects of both strong and …

Physiology of the respiratory drive in ICU patients: implications for diagnosis and treatment

AH Jonkman, HJ De Vries, LMA Heunks - Critical Care, 2020 - Springer
This article is one of ten reviews selected from the Annual Update in Intensive Care and
Emergency Medicine 2020. Other selected articles can be found online at https://www …

Advanced point-of-care bedside monitoring for acute respiratory failure

G Cammarota, R Simonte, F Longhini, S Spadaro… - …, 2023 - pubs.asahq.org
Advanced respiratory monitoring involves several mini-or noninvasive tools, applicable at
bedside, focused on assessing lung aeration and morphology, lung recruitment and …

Oxygenation strategies during flexible bronchoscopy: a review of the literature

C Pelaia, A Bruni, E Garofalo, S Rovida, E Arrighi… - Respiratory …, 2021 - Springer
During flexible fiberoptic bronchoscopy (FOB) the arterial partial pressure of oxygen can
drop, increasing the risk for respiratory failure. To avoid desaturation episodes during the …

High-flow nasal cannula oxygen therapy for outpatients undergoing flexible bronchoscopy: a randomised controlled trial

F Longhini, C Pelaia, E Garofalo, A Bruni, R Placida… - Thorax, 2022 - thorax.bmj.com
Introduction High-flow nasal cannula (HFNC) provides benefits to patients undergoing
flexible bronchoscopy (FOB). We compared the effects of HFNC versus standard therapy …

Ventilator-induced lung injury during controlled ventilation in patients with acute respiratory distress syndrome: less is probably better

FF Cruz, L Ball, PRM Rocco, P Pelosi - Expert review of respiratory …, 2018 - Taylor & Francis
Introduction: Mechanical ventilation is required to support respiratory function in the acute
respiratory distress syndrome (ARDS), but it may promote lung damage, a phenomenon …

Is my patient's respiratory drive (too) high?

I Telias, L Brochard, EC Goligher - Intensive care medicine, 2018 - Springer
The intensity of the neural stimulus to breathe is called “respiratory drive”[1] and plays a
major role in acute respiratory failure before, during, and after mechanical ventilation …

High-flow nasal cannula for reducing hypoxemic events in patients undergoing bronchoscopy: A systematic review and meta-analysis of randomized trials

CL Su, LL Chiang, KW Tam, TT Chen, MC Hu - PLoS One, 2021 - journals.plos.org
Background Patients undergoing bronchoscopic procedures may develop hypoxemia and
severe complications. High-flow nasal cannula (HFNC) may prevent hypoxemic events …