Kainate receptor antagonists: recent advances and therapeutic perspective
P Chałupnik, E Szymańska - International Journal of Molecular Sciences, 2023 - mdpi.com
Since the 1990s, ionotropic glutamate receptors have served as an outstanding target for
drug discovery research aimed at the discovery of new neurotherapeutic agents. With the …
drug discovery research aimed at the discovery of new neurotherapeutic agents. With the …
Discovery of the first highly selective antagonist of the GluK3 kainate receptor subtype
P Chałupnik, A Vialko, DS Pickering… - International Journal of …, 2022 - mdpi.com
Kainate receptors belong to the family of glutamate receptors ion channels, which are
responsible for the majority of rapid excitatory synaptic transmission in the central nervous …
responsible for the majority of rapid excitatory synaptic transmission in the central nervous …
Domoic Acid as a Lead for the Discovery of the First Selective Ligand for Kainate Receptor Subtype 5 (GluK5)
S Buschbom-Helmke, P Wang, A Alcaide… - Journal of Medicinal …, 2024 - ACS Publications
Twenty-one simplified analogues of the natural product domoic acid were designed,
synthesized, and then characterized at homomeric kainic acid (KA) receptors (GluK1-3, 5) …
synthesized, and then characterized at homomeric kainic acid (KA) receptors (GluK1-3, 5) …
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P Chałupnik, A Vialko, DS Pickering, M Hinkkanen… - TC - ruj.uj.edu.pl
Kainate receptors belong to the family of glutamate receptors ion channels, which are
responsible for the majority of rapid excitatory synaptic transmission in the central nervous …
responsible for the majority of rapid excitatory synaptic transmission in the central nervous …