The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …

The mitotic spindle has a crucial role in ensuring the accurate segregation of chromosomes
into the two daughter cells during cell division, which is paramount for maintaining genome …

Mosaic loss of chromosome Y (LOY) in circulating white blood cells is the most common
form of clonal mosaicism,,,–, yet our knowledge of the causes and consequences of this is …

Phase separation of substrates and effectors is proposed to enhance biological reaction
rates and efficiency. Targeting protein for Xklp2 (TPX2) is an effector of branching …

Centrosomes catalyse the formation of microtubules needed to assemble the mitotic spindle
apparatus. Centrosomes themselves duplicate once per cell cycle, in a process that is …

Meiotic spindle assembly ensures proper chromosome segregation in oocytes. However,
the mechanisms behind spindle assembly in human oocytes remain largely unknown. We …

Microtubules play crucial roles in cellular architecture, intracellular transport, and mitosis.
The availability of free tubulin subunits affects polymerization dynamics and microtubule …

Interactions between biomolecules control the processes of life in health and their
malfunction in disease, making their characterization and quantification essential …

Fertilizable eggs develop from diploid precursor cells termed oocytes. Once every menstrual
cycle, an oocyte matures into a fertilizable egg in the ovary. To this end, the oocyte …

Microtubules control cell architecture by serving as a scaffold for intracellular transport,
signaling, and organelle positioning. Microtubules are intrinsically polarized, and their …