Identification of promising inhibitors against breast cancer disease by targeting NUDIX hydrolase 5 (NUDT5) biomolecule
NM Almansour - Journal of Biomolecular Structure and Dynamics, 2025 - Taylor & Francis
It is well documented that NUDT5 enzyme inhibition in breast cancer cell lines arrest cancer
cells growth, invasiveness and migration. The NUDT5 enzyme enhances breast cancer …
cells growth, invasiveness and migration. The NUDT5 enzyme enhances breast cancer …
Identification of potential NUDT5 inhibitors from marine bacterial natural compounds via molecular dynamics and free energy landscape analysis
Abstract NUDIX hydrolase 5 (NUDT5) is an enzyme involved in the hydrolysis of nucleoside
diphosphates linked to other moieties, such as ADP-ribose. This cofactor is vital in redox …
diphosphates linked to other moieties, such as ADP-ribose. This cofactor is vital in redox …
Repurposing fluvoxamine as an inhibitor for NUDT5 in breast cancer cell: an in silico and in vitro study
Drug repurposing is necessary to accelerate drug discovery and meet the drug needs. This
study investigated the possibility of using fluvoxamine to inhibit the cellular metabolizing …
study investigated the possibility of using fluvoxamine to inhibit the cellular metabolizing …
Targeting Nudix Hydrolase 5 with Bioactive Flavonoids: Molecular Dynamics and Docking Studies for Breast Cancer Therapy
S Dhanasekaran, PP Selvadoss… - Cell Biochemistry and …, 2024 - Springer
Breast cancer (BC) is the most prevalent malignancy among women globally and the
leading cause of cancer-related mortality. Consequently, there is an urgent need for new …
leading cause of cancer-related mortality. Consequently, there is an urgent need for new …