RTS,S/AS01 malaria vaccine (Mosquirix®): a profile of its use

YY Syed - Drugs & Therapy Perspectives, 2022 - Springer
Abstract RTS, S/AS01 (Mosquirix®) is a vaccine against malaria caused by Plasmodium
falciparum. In a phase 3 trial, RTS, S/AS01 showed vaccine efficacy against clinical malaria …

Impacts of ecology, parasite antigenic variation, and human genetics on RTS, S/AS01e malaria vaccine efficacy

GJ Bell, ST Agnandji, KP Asante, A Ghansah… - Current Epidemiology …, 2021 - Springer
Abstract Purpose of Review Global malaria elimination has little chance of success without
an effective vaccine. The first malaria vaccine, RTS, S/AS01e, demonstrated moderate …

Malaria transmission intensity likely modifies RTS, S/AS01 efficacy due to a rebound effect in Ghana, Malawi, and Gabon

GJ Bell, V Goel, P Essone, D Dosoo… - The Journal of …, 2022 - academic.oup.com
Abstract Background RTS, S/AS01 is the first malaria vaccine to be approved and
recommended for widespread implementation by the World Health Organization (WHO) …

[HTML][HTML] Modelling the relative cost-effectiveness of the RTS, S/AS01 malaria vaccine compared to investment in vector control or chemoprophylaxis

HM Topazian, N Schmit, I Gerard-Ursin, GD Charles… - Vaccine, 2023 - Elsevier
Abstract Background The World Health Organization has recommended a 4-dose schedule
of the RTS, S/AS01 (RTS, S) vaccine for children in regions of moderate to high P …

Impact of high human genetic diversity in Africa on immunogenicity and efficacy of RTS, S/AS01 vaccine

S Tukwasibwe, G Mboowa, I Sserwadda… - Immunogenetics, 2023 - Springer
In modern medicine, vaccination is one of the most effective public health strategies to
prevent infectious diseases. Indisputably, vaccines have saved millions of lives by reducing …

[HTML][HTML] Malaria Burden Stratification in Malawi-A report of a consultative workshop to inform the 2023-2030 Malawi Malaria Strategic Plan

D Mategula, C Mitambo, W Sheahan… - Wellcome Open …, 2023 - ncbi.nlm.nih.gov
Background: Malawi's National Malaria Control Programme (NMCP) is developing a new
strategic plan for 2023-2030 to combat malaria and recognizes that a blanket approach to …

Analysis of the potential for a malaria vaccine to reduce gaps in malaria intervention coverage

HJT Unwin, L Mwandigha, P Winskill, AC Ghani… - Malaria journal, 2021 - Springer
Abstract Background The RTS, S/AS01 malaria vaccine is currently being evaluated in a
cluster-randomized pilot implementation programme in three African countries. This study …

Environmental modifiers of RTS, S/AS01 malaria vaccine efficacy in Lilongwe, Malawi

GJ Bell, MS Loop, T Mvalo, JJ Juliano, I Mofolo… - BMC Public Health, 2020 - Springer
Abstract Background RTS, S/AS01 is the first vaccine against malaria to undergo pilot
implementation, beginning in 2019 and vaccinating 360,000 children per year in Malawi …

Equity-Informative Economic Evaluations of Vaccines: A Systematic Literature Review

C Patikorn, JY Cho, P Lambach, R Hutubessy… - Vaccines, 2023 - mdpi.com
The Immunization Agenda 2030 prioritizes the populations without access to vaccines.
Health equity has been increasingly incorporated into economic evaluations of vaccines to …

An Investment Case for the Scale-up and Use of Insecticide-Treated Nets Halfway into the SDG Targets

R Shretta, RN Anye - Journal of Benefit-Cost Analysis, 2023 - cambridge.org
This article examines a policy of scaling up LLINs by 10 percentage points from 2020 levels
with a 90% cap in the 29 highest-burden countries in Africa along with social and behavioral …