The mammary gland: basic structure and molecular signaling during development

SK Biswas, S Banerjee, GW Baker, CY Kuo… - International Journal of …, 2022 - mdpi.com
The mammary gland is a compound, branched tubuloalveolar structure and a major
characteristic of mammals. The mammary gland has evolved from epidermal apocrine …

miR-212/132 expression and functions: within and beyond the neuronal compartment

A Wanet, A Tacheny, T Arnould… - Nucleic acids …, 2012 - academic.oup.com
During the last two decades, microRNAs (miRNAs) emerged as critical regulators of gene
expression. By modulating the expression of numerous target mRNAs mainly at the post …

The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy

A Ucar, SK Gupta, J Fiedler, E Erikci… - Nature …, 2012 - nature.com
Pathological growth of cardiomyocytes (hypertrophy) is a major determinant for the
development of heart failure, one of the leading medical causes of mortality worldwide. Here …

miRWalk database for miRNA–target interactions

H Dweep, N Gretz, C Sticht - RNA mapping: methods and protocols, 2014 - Springer
Abstract miRWalk (http://mirwalk. uni-hd. de/) is a publicly available comprehensive
resource, hosting the predicted as well as the experimentally validated microRNA (miRNA) …

MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach

VN Parikh, RC Jin, S Rabello, N Gulbahce, K White… - Circulation, 2012 - Am Heart Assoc
Background—Pulmonary hypertension (PH) is driven by diverse pathogenic etiologies.
Owing to their pleiotropic actions, microRNA molecules are potential candidates for …

Potent degradation of neuronal mi RNA s induced by highly complementary targets

M de la Mata, D Gaidatzis, M Vitanescu, MB Stadler… - EMBO …, 2015 - embopress.org
Micro RNA s (mi RNA s) regulate target mRNA s by silencing them. Reciprocally, however,
target mRNA s can also modulate mi RNA stability. Here, we uncover a remarkable efficacy …

MicroRNAs in neurodegenerative diseases

S Quinlan, A Kenny, M Medina, T Engel… - International review of …, 2017 - Elsevier
MicroRNAs are small noncoding RNAs that regulate gene expression at the
posttranscriptional level in a sequence-specific manner. After their discovery in 1993 …

Integrated morphodynamic signalling of the mammary gland

N Gjorevski, CM Nelson - Nature reviews Molecular cell biology, 2011 - nature.com
The mammary gland undergoes a spectacular series of changes as it develops, and
maintains a remarkable capacity to remodel and regenerate for several decades. Mammary …

Macrophages and fibroblasts, key players in cancer chemoresistance

LV Ireland, A Mielgo - Frontiers in cell and developmental biology, 2018 - frontiersin.org
Chemotherapy is routinely used in cancer treatment to eliminate primary and metastatic
tumor cells. However, tumors often display or develop resistance to chemotherapy …

MicroRNA-132 attenuates cerebral injury by protecting blood-brain-barrier in MCAO mice

X Zuo, J Lu, A Manaenko, X Qi, J Tang, Q Mei… - Experimental …, 2019 - Elsevier
MicroRNAs (miRNAs) have been widely reported to induce posttranscriptional gene
silencing and led to an explosion of new strategies for the treatment of human disease. It has …