Membrane-intercalating conjugated oligoelectrolytes

C Zhou, GWN Chia, KT Yong - Chemical Society Reviews, 2022 - pubs.rsc.org
By acting as effective biomimetics of the lipid bilayers, membrane-intercalating conjugated
oligoelectrolytes (MICOEs) can spontaneously insert themselves into both synthetic lipid …

Optical membrane control with red light enabled by red-shifted photolipids

SD Pritzl, DB Konrad, MF Ober, AF Richter, JA Frank… - Langmuir, 2021 - ACS Publications
Photoswitchable phospholipids, or “photolipids”, that harbor an azobenzene group in their
lipid tails are versatile tools to manipulate and control lipid bilayer properties with light. So …

Reversible and size-controlled assembly of reflectin proteins using a charged azobenzene photoswitch

CM Tobin, R Gordon, SK Tochikura, BF Chmelka… - Chemical …, 2024 - pubs.rsc.org
Disordered proteins often undergo a stimuli-responsive, disorder-to-order transition which
facilitates dynamic processes that modulate the physiological activities and material …

N-Arylimidazoliums as Highly Selective Biomimetic Antimicrobial Agents

Q Kong, G Li, F Zhang, T Yu, X Chen… - Journal of Medicinal …, 2022 - ACS Publications
Antibiotic resistance has become one of the greatest health threats in the world. In this study,
a charge-dispersed dimerization strategy is described for the antimicrobial peptide (AMP) …

Unique iminotetrahydroberberine-corbelled metronidazoles as potential membrane active broad-spectrum antibacterial agents

MF Ansari, YM Tan, H Sun, S Li, CH Zhou - Bioorganic & Medicinal …, 2022 - Elsevier
In an effort for fighting with dreadful drug resistance, iminotetraberberine was hybridized with
metronidazole to construct a unique type of potential broad-spectrum antibacterial …

[HTML][HTML] Light-triggered cardiac microphysiological model

V Vurro, K Shani, HAM Ardoña, JF Zimmerman… - APL …, 2023 - pubs.aip.org
Light is recognized as an accurate and noninvasive tool for stimulating excitable cells. Here,
we report on a non-genetic approach based on organic molecular phototransducers that …

Backbone flexibility/amphiphilicity modulation of AIE active polyelectrolytes for mitochondria-and nucleus-targeted synergistic photodynamic therapy of cancer cells

Z He, X Han, Z Yan, B Guo, Q Cai, Y Yao - Materials Chemistry …, 2022 - pubs.rsc.org
Mitochondria-and nucleus-targeted photodynamic therapy (PDT) to locally destruct
organelles that play vital roles in physiologic processes holds great promise. Notably, the …

Antimicrobial Conjugated Oligoelectrolytes Containing Triphenylphosphonium Solubilizing Groups

SJW Chan, K Zhang, JY Zhu… - Chemistry–A European …, 2023 - Wiley Online Library
Conjugated oligoelectrolytes (COEs) are an emerging class of amphiphilic antimicrobial
compounds with a modular molecular framework suitable for simple chemical derivatization …

Synthesis, solubility and optical properties of π-conjugated oligoelectrolytes derived from bis-thiophene-dialkoxyphenylene derivatives

C Simon, D Mathilde, J Thibaut, N Claude… - New Journal of …, 2023 - pubs.rsc.org
A new family of well-defined and fully conjugated oligoelectrolyte compounds were
elaborated based on one or two bis-thiophene dialkoxyphenylene units. Di-or tetra …

Rational Design and Synthesis of Membrane-Active Conjugated Oligoelectrolytes for Biological Applications

J Limwongyut - 2022 - search.proquest.com
Lipid bilayers are omnipresent in biological systems as a barrier protecting intracellular
components from the external environment. The semi-permeable behavior of membranes …