Diversity of molecular targets and signaling pathways for CBD

DL de Almeida, LA Devi - Pharmacology research & …, 2020 - Wiley Online Library
Cannabidiol (CBD) is the second most abundant component of the Cannabis plant and is
known to have effects distinct from Δ9‐tetrahydrocannabinol (THC). Many studies that …

Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives

A Kumari, RK Singh - Bioorganic chemistry, 2019 - Elsevier
Indole is a versatile pharmacophore, a privileged scaffold and an outstanding heterocyclic
compound with wide ranges of pharmacological activities due to different mechanisms of …

Molecular and pharmacological aspects of piperine as a potential molecule for disease prevention and management: evidence from clinical trials

AK Tripathi, AK Ray, SK Mishra - Beni-Suef university journal of basic and …, 2022 - Springer
Background Piperine is a type of amide alkaloid that exhibits pleiotropic properties like
antioxidant, anticancer, anti-inflammatory, antihypertensive, hepatoprotective …

Regulation of long-chain polyunsaturated fatty acid biosynthesis in teleost fish

D Xie, C Chen, Y Dong, C You, S Wang… - Progress in Lipid …, 2021 - Elsevier
Abstract Omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA, C 20-24),
including eicosapentaenoic acid (EPA, 20: 5n-3) and docosahexaenoic acid (DHA, 22: 6n …

Protective Effects of (E)-β-Caryophyllene (BCP) in Chronic Inflammation

R Scandiffio, F Geddo, E Cottone, G Querio… - Nutrients, 2020 - mdpi.com
(E)-β-caryophyllene (BCP) is a bicyclic sesquiterpene widely distributed in the plant
kingdom, where it contributes a unique aroma to essential oils and has a pivotal role in the …

Cinnamic acid and its derivatives: mechanisms for prevention and management of diabetes and its complications

S Adisakwattana - Nutrients, 2017 - mdpi.com
With recent insight into the development of dietary supplements and functional foods, search
of effective phytochemical compounds and their mechanisms involved in prevention and …

[HTML][HTML] Aberrant hepatic lipid metabolism associated with gut microbiota dysbiosis triggers hepatotoxicity of novel PFOS alternatives in adult zebrafish

Q Wang, J Huang, S Liu, C Wang, Y Jin, H Lai… - Environment …, 2022 - Elsevier
Perfluorooctane sulfonate (PFOS) has been reported to induce hepatotoxicity in wildlife and
humans. Novel PFOS alternatives have been widely used following restrictions on PFOS …

Regulation of glycolysis by non-coding RNAs in cancer: switching on the Warburg effect

H Mirzaei, MR Hamblin - Molecular Therapy-Oncolytics, 2020 - cell.com
The" Warburg effect" describes the reprogramming of glucose metabolism away from
oxidative phosphorylation toward aerobic glycolysis, and it is one of the hallmarks of cancer …

Tissue engineering of skin and regenerative medicine for wound care

ST Boyce, AL Lalley - Burns & trauma, 2018 - academic.oup.com
Background Advances in burn care during the recent past have included improvements in
fluid resuscitation, early wound excision, respiratory support and management of inhalation …

Peroxisome proliferator-activated receptor γ (PPARγ): A master gatekeeper in CNS injury and repair

W Cai, T Yang, H Liu, L Han, K Zhang, X Hu… - Progress in …, 2018 - Elsevier
Peroxisome proliferator-activated receptor γ (PPARγ) is a widely expressed ligand-
modulated transcription factor that governs the expression of genes involved in …