Pyrimidines are nitrogen-containing heterocycles known for anticancer, anti-HIV, antifungal,
and antibacterial activities. Pyrimidines, compounds bearing this heterocycle, are common …

Nucleoside analogues (NAs) are a family of compounds which include a variety of purine
and pyrimidine derivatives, widely used as anticancer and antiviral agents. For their ability to …

To achieve new breakthroughs in the development of synergistic antiviral medication
cocrystals of acyclovir (AYL) with phenolic acids, a cocrystallization-driven strategy for …

A series of 3-phosphonylated thiazolo [3, 2-a] oxopyrimidines 3a-k was synthesized for the
first time by the reactions of chloroethynylphosphonates with 5, 6-disubstituted 2-thiouracils …

A new chemical library based on the hybridization of cholic acid with the heterocyclic moiety
1, 3, 4-oxadizole was synthesized, and tested for antimicrobial activity against Gram …

Since the beginning of the coronavirus pandemic in late 2019, viral infections have become
one of the top three causes of mortality worldwide. Immunization and the use of …

To date, viruses are known to cause chronic to acute pathogenesis. Nevertheless, antiviral
drugs have been known for their medicinal applications for the last few decades to treat …

A versatile and simple spectrophotometric technique has been presented for the detection of
Ganciclovir (GANCICLOVIR) in pharmaceutical formulations. The oxidation method included …

Diseases caused by bacteria are a big challenge for scientists worldwide. These bacteria
can be resistant through the adaption of new ways to protect themselves against …

Актуальность темы исследования. Идеальное лекарственное средство должно
обладать максимальной селективностью к своей мишени в организме человека в …