Parkinson's disease: from pathogenesis to pharmacogenomics

R Cacabelos - International journal of molecular sciences, 2017 - mdpi.com
Parkinson's disease (PD) is the second most important age-related neurodegenerative
disorder in developed societies, after Alzheimer's disease, with a prevalence ranging from …

[HTML][HTML] Unmet needs in Parkinson disease: Motor and non-motor

PA LeWitt, KR Chaudhuri - Parkinsonism & Related Disorders, 2020 - Elsevier
Compared to other neurodegenerative diseases, Parkinson's disease (PD) is distinctive in
terms of marked symptomatic variability and prognosis, as well as for the wide variety of …

An update on the safety of current therapies for Alzheimer's disease: focus on rivastigmine

R Khoury, J Rajamanickam… - … advances in drug …, 2018 - journals.sagepub.com
Alzheimer's disease (AD) is the most common cause of major neurocognitive disorders
worldwide. Despite all research efforts, therapeutic options for AD are still limited to two drug …

Managing gait, balance, and posture in Parkinson's disease

B Debû, C De Oliveira Godeiro, JC Lino… - Current neurology and …, 2018 - Springer
Abstract Purpose of Review Postural instability and gait difficulties inexorably worsen with
Parkinson's disease (PD) progression and become treatment resistant, with a severe impact …

A low-cost vision system based on the analysis of motor features for recognition and severity rating of Parkinson's Disease

D Buongiorno, I Bortone, GD Cascarano… - BMC Medical Informatics …, 2019 - Springer
Background Assessment and rating of Parkinson's Disease (PD) are commonly based on
the medical observation of several clinical manifestations, including the analysis of motor …

Automated and accurate assessment for postural abnormalities in patients with Parkinson's disease based on Kinect and machine learning

Z Zhang, R Hong, A Lin, X Su, Y Jin, Y Gao… - Journal of …, 2021 - Springer
Background Automated and accurate assessment for postural abnormalities is necessary to
monitor the clinical progress of Parkinson's disease (PD). The combination of depth camera …

An artificial neural network approach to detect presence and severity of Parkinson's disease via gait parameters

T Varrecchia, SF Castiglia, A Ranavolo, C Conte… - PLoS …, 2021 - journals.plos.org
Introduction Gait deficits are debilitating in people with Parkinson's disease (PwPD), which
inevitably deteriorate over time. Gait analysis is a valuable method to assess disease …

Task force consensus on nosology and cut‐off values for axial postural abnormalities in parkinsonism

M Tinazzi, C Geroin, R Bhidayasiri… - Movement Disorders …, 2022 - Wiley Online Library
Background There is no consensus with regard to the nosology and cut‐off values for
postural abnormalities in parkinsonism. Objective To reach a consensus regarding the …

Prevalence of axial postural abnormalities and their subtypes in Parkinson's disease: A systematic review and meta-analysis

S Cao, Y Cui, J Jin, F Li, X Liu, T Feng - Journal of Neurology, 2023 - Springer
Background and purpose Axial postural abnormalities, mainly involving the spinal
deformities, are disabling symptoms of Parkinson's disease (PD). However, the prevalence …

Clinical manifestations of Parkinson disease

KL Chou - UpToDate, fev, 2020 - uptodate.com
Parkinson disease (PD) is an adult-onset progressive neurodegenerative disorder, first
described as" Shaking palsy" over 200 years ago by James Parkinson [1]. While traditionally …