Parkinson's disease prevalence is rapidly increasing in an aging global population. With this
increase comes exponentially rising social and economic costs, emphasizing the immediate …

The blood‐brain barrier (BBB), as a crucial gate of brain‐blood molecular exchange, is
involved in the pathogenesis of multiple neurological diseases. Oxidative stress is caused …

Cu/Zn superoxide dismutase (SOD1) is a frontline antioxidant enzyme catalysing superoxide
breakdown and is important for most forms of eukaryotic life. The evolution of aerobic …

Aberrant self-assembly and toxicity of wild-type and mutant superoxide dismutase 1 (SOD1)
has been widely examined in silico, in vitro and in transgenic animal models of amyotrophic …

Background Alzheimer's disease (AD) is the commonest cause of dementia, with
approximately 5 million new cases occurring annually. Despite decades of research, its …

Zinc, an essential micronutrient for life, was first discovered in 1869 and later found to be
indispensable for the normal development of plants and for the normal growth of rats and …

Vesicular transporters (VTs) define the type of neurotransmitter that synaptic vesicles (SVs)
store and release. While certain mammalian neurons release multiple transmitters, it is not …

Many central nervous system (CNS) diseases are still incurable and only symptomatic
treatments are available. Oxidative stress is suggested to be a common hallmark, being able …

We aimed to examine the molecular basis of the positive effect of resveratrol against
amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD), cognitive impairment (CI) …

In this review we give an updated outlook of the reactivity of catecholamines, particularly
dopamine, and the redox effects produced by their interaction with copper (II) and dioxygen …