In this era of efficacious antiretroviral therapy and consequent immune reconstitution,
oropharyngeal and esophageal candidiasis (OPC and OEC) still remain two clinically …

Antibiobodies are paradigmatic of yeast killer toxin (KT)-like antibodies (KAbs) mimicking the
antimicrobial activity of KTs in the frame of the yeast killer phenomenon. Polyclonal …

Background Complementarity-determining regions (CDRs) are immunoglobulin (Ig)
hypervariable domains that determine specific antibody (Ab) binding. We have shown that …

Background/Aims: New antivirals are needed to supplement or replace currently used drugs.
The aim of this study was to evaluate the antiviral activity of synthetic peptides derived from …

Complementarity-determining regions (CDRs) from monoclonal antibodies tested as
synthetic peptides display anti-infective and antitumor activities, independent of the …

Background It has been documented that, independently from the specificity of the native
antibody (Ab) for a given antigen (Ag), complementarity determining regions (CDR)-related …

Abstract “Antibiobodies”, antibodies (Abs) with antibiotic activity, internal image of a Pichia
anomala killer toxin (Pa KT) characterized by microbicidal activity against microorganisms …

Effective delivery is a critical issue in the use of conventional free drugs. Studies on the
structure− function relationship of a therapeutic antibody-derived candidacidal decapeptide …

The incidence of life-threatening viral and microbial infections has dramatically increased
over recent decades. Despite significant developments in anti-infective chemotherapy, many …

Antibodies (Abs), often associated with antimicrobial and antitumor agents, have emerged
as an important class of novel drugs for antigen-driven therapeutic purposes in diverse …