More than 40 antimicrobial peptides and proteins (AMPs) are expressed in the oral cavity.
These AMPs have been organized into 6 functional groups, 1 of which, cationic AMPs, has …

A grand challenge in the field of structural biology is to design and engineer proteins that
exhibit targeted functions. Although much success on this front has been achieved, design …

Short peptides have attracted significant attention from researchers in the past few years due
to their easy design, synthesis and characterization, diverse functionalisation possibilities …

Recent studies have shown that antimicrobial peptides (AMPs) can self-assemble into
supramolecular structures, but this has been overlooked as causative of their antimicrobial …

Microorganisms within the marine environment have been shown to be very effective
sources of naturally produced antimicrobial peptides (AMPs). Several nonribosomal …

Poly-peptide molecules have shown promising applications in drug delivery and tumor
targeting. A series of tumor homing peptides were designed by exhaustively sampling low …

Amyloid diseases are linked to protein misfolding whereby the amyloidogenic protein
undergoes a conformational change, aggregates and eventually forms amyloid fibrils. While …

There is now substantial evidence that soluble oligomers are primary toxic agents in amyloid
diseases. The development of an antibody recognizing the toxic soluble oligomeric forms of …

Intrinsically disordered protein (IDP) conformers occupy large regions of conformational
space and display relatively flat energy surfaces. Amyloid-forming IDPs, unlike natively …

Nosocomial infections affect hundreds of millions of patients worldwide each year, and~
60% of these infections are associated with biofilm formation on an implanted medical …