Causal relationships involving brain imaging-derived phenotypes based on UKB imaging cohort: a review of Mendelian randomization studies
M Wang, Z Wang, Y Wang, Q Zhou… - Frontiers in Neuroscience, 2024 - frontiersin.org
The UK Biobank (UKB) has the largest adult brain imaging dataset, which encompasses
over 40,000 participants. A significant number of Mendelian randomization (MR) studies …
over 40,000 participants. A significant number of Mendelian randomization (MR) studies …
The genetic architecture of multimodal human brain age
The complex biological mechanisms underlying human brain aging remain incompletely
understood. This study investigated the genetic architecture of three brain age gaps (BAG) …
understood. This study investigated the genetic architecture of three brain age gaps (BAG) …
The Genetic Heterogeneity of Multimodal Human Brain Age
The complex biological mechanisms underlying human brain aging remain incompletely
understood, involving multiple body organs and chronic diseases. In this study, we used …
understood, involving multiple body organs and chronic diseases. In this study, we used …
[HTML][HTML] Assessing the association between global structural brain age and polygenic risk for schizophrenia in early adulthood: A recall-by-genotype study
C Constantinides, V Baltramonaityte, D Caramaschi… - cortex, 2024 - Elsevier
Neuroimaging studies consistently show advanced brain age in schizophrenia, suggesting
that brain structure is often 'older'than expected at a given chronological age. Whether …
that brain structure is often 'older'than expected at a given chronological age. Whether …
Dimensions of early life adversity are differentially associated with patterns of delayed and accelerated brain maturation
Background Different types of early-life adversity have been associated with children's brain
structure and function. However, understanding the disparate influence of distinct adversity …
structure and function. However, understanding the disparate influence of distinct adversity …
Genome-wide analysis of brain age identifies 25 associated loci and unveils relationships with mental and physical health
Neuroimaging and machine learning are opening up new opportunities in studying
biological aging mechanisms. In this field,'brain age gap'has emerged as promising MRI …
biological aging mechanisms. In this field,'brain age gap'has emerged as promising MRI …