Role of genomics in combating COVID-19 pandemic

KA Saravanan, M Panigrahi, H Kumar, D Rajawat… - Gene, 2022 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) quickly swept over the world, becoming
one of the most devastating outbreaks in human history. Being the first pandemic in the post …

[HTML][HTML] A Review of Current In Silico Methods for Repositioning Drugs and Chemical Compounds

B He, F Hou, C Ren, P Bing, X Xiao - Frontiers in Oncology, 2021 - frontiersin.org
Drug repositioning is a new way of applying the existing therapeutics to new disease
indications. Due to the exorbitant cost and high failure rate in developing new drugs, the …

A deep learning method for repurposing antiviral drugs against new viruses via multi-view nonnegative matrix factorization and its application to SARS-CoV-2

X Su, L Hu, Z You, P Hu, L Wang… - Briefings in …, 2022 - academic.oup.com
The outbreak of COVID-19 caused by SARS-coronavirus (CoV)-2 has made millions of
deaths since 2019. Although a variety of computational methods have been proposed to …

VDA-RWLRLS: An anti-SARS-CoV-2 drug prioritizing framework combining an unbalanced bi-random walk and Laplacian regularized least squares

L Shen, F Liu, L Huang, G Liu, L Zhou… - Computers in biology and …, 2022 - Elsevier
Background A new coronavirus disease named COVID-19, caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), is rapidly spreading worldwide …

[HTML][HTML] Efficacy of oseltamivir in the treatment of patients infected with Covid-19

A Zendehdel, M Bidkhori, M Ansari… - Annals of Medicine and …, 2022 - Elsevier
Objective The recent unprecedented pandemic caused by Sars-Cov-2 (the new coronavirus
2019), is threatening public health around the world. Although several studies have been …

[HTML][HTML] Evaluation of the MGISEQ-2000 sequencing platform for Illumina target capture sequencing libraries

J Lang, R Zhu, X Sun, S Zhu, T Li, X Shi, Y Sun… - Frontiers in …, 2021 - frontiersin.org
Illumina is the leading sequencing platform in the next-generation sequencing (NGS) market
globally. In recent years, MGI Tech has presented a series of new sequencers, including …

[HTML][HTML] A new integrated framework for the identification of potential virus–drug associations

J Qu, Z Song, X Cheng, Z Jiang, J Zhou - Frontiers in Microbiology, 2023 - frontiersin.org
Introduction With the increasingly serious problem of antiviral drug resistance, drug
repurposing offers a time-efficient and cost-effective way to find potential therapeutic agents …

[HTML][HTML] Discovery of potential therapeutic drugs for covid-19 through logistic matrix factorization with kernel diffusion

X Tian, L Shen, P Gao, L Huang, G Liu, L Zhou… - Frontiers in …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is rapidly spreading. Researchers around the world
are dedicated to finding the treatment clues for COVID-19. Drug repositioning, as a rapid …

[HTML][HTML] Neighborhood-based inference and restricted Boltzmann machine for microbe and drug associations prediction

X Cheng, J Qu, S Song, Z Bian - PeerJ, 2022 - peerj.com
Background Efficient identification of microbe-drug associations is critical for drug
development and solving problem of antimicrobial resistance. Traditional wet-lab method …

[HTML][HTML] DRaW: prediction of COVID-19 antivirals by deep learning—an objection on using matrix factorization

SM Hashemi, A Zabihian, M Hooshmand… - BMC …, 2023 - Springer
Background Due to the high resource consumption of introducing a new drug, drug
repurposing plays an essential role in drug discovery. To do this, researchers examine the …