Attention deficit hyperactivity disorder (ADHD) is a polygenic neurodevelopmental disorder
that affects 8–12% of children and> 4% of adults. Environmental factors are believed to …

The term “cerebral palsy mimic” is used to describe a number of neurogenetic disorders that
may present with motor symptoms in early childhood, resulting in a misdiagnosis of cerebral …

The mammalian brain is composed of diverse, specialized cell populations. To
systematically ascertain and learn from these cellular specializations, we used Drop-seq to …

Creatine is pivotal in energy metabolism of muscle and brain cells, both in physiological and
in pathological conditions. Additionally, creatine facilitates the differentiation of muscle and …

Background & Aims Patients with inflammatory bowel diseases (IBDs) have intestinal barrier
dysfunction. Creatine regulates energy distribution within cells and reduces the severity of …

Autism spectrum disorders (ASDs) are a group of neurodevelopment disorders
characterized by childhood onset deficits in social communication and interaction. Although …

Although norm-referenced scores are essential to the identification of disability, they
possess several features which affect their sensitivity to change. Norm-referenced scores …

Creatine transporter deficiency was discovered in 2001 as an X-linked cause of intellectual
disability characterized by cerebral creatine deficiency. This review describes the current …

Creatine is an essential metabolite for the storage and rapid supply of energy in muscle and
nerve cells. In humans, impaired metabolism, transport, and distribution of creatine …

Currently there are 91 treatable inborn errors of metabolism that cause intellectual
developmental disorders. Cerebral creatine deficiencies (CDD) comprise three of these …