The Paneth cell: the curator and defender of the immature small intestine

SR Lueschow, SJ McElroy - Frontiers in immunology, 2020 - frontiersin.org
Paneth cells were first described in the late 19th century by Gustav Schwalbe and Josef
Paneth as columnar epithelial cells possessing prominent eosinophilic granules in their …

Can probiotics modulate human disease by impacting intestinal barrier function?

PA Bron, M Kleerebezem, RJ Brummer… - British Journal of …, 2017 - cambridge.org
Intestinal barrier integrity is a prerequisite for homeostasis of mucosal function, which is
balanced to maximise absorptive capacity, while maintaining efficient defensive reactions …

Defining dysbiosis and its influence on host immunity and disease

C Petersen, JL Round - Cellular microbiology, 2014 - Wiley Online Library
Mammalian immune system development depends on instruction from resident commensal
microorganisms. Diseases associated with abnormal immune responses towards …

Longitudinal evaluation of fecal microbiota transplantation for ameliorating calf diarrhea and improving growth performance

HS Kim, TW Whon, H Sung, YS Jeong, ES Jung… - Nature …, 2021 - nature.com
Calf diarrhea is associated with enteric infections, and also provokes the overuse of
antibiotics. Therefore, proper treatment of diarrhea represents a therapeutic challenge in …

Oxygen as a driver of gut dysbiosis

F Rivera-Chávez, CA Lopez, AJ Bäumler - Free Radical Biology and …, 2017 - Elsevier
Abstract Changes in the composition of gut-associated microbial communities may underlie
many inflammatory and allergic diseases. However, the processes that help maintain a …

A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice

TR Chiaro, R Soto, W Zac Stephens… - Science translational …, 2017 - science.org
The commensal microbiota has an important impact on host health, which is only beginning
to be elucidated. Despite the presence of fungal, archaeal, and viral members, most studies …

Microbiota changes induced by microencapsulated sodium butyrate in patients with inflammatory bowel disease

S Facchin, N Vitulo, M Calgaro, A Buda… - …, 2020 - Wiley Online Library
Background Butyrate has shown anti‐inflammatory and regenerative properties, providing
symptomatic relief when orally supplemented in patients suffering from various colonic …

Protective microbiota: from localized to long-reaching co-immunity

L Chiu, T Bazin, ME Truchetet… - Frontiers in …, 2017 - frontiersin.org
Resident microbiota do not just shape host immunity, they can also contribute to host
protection against pathogens and infectious diseases. Previous reviews of the protective …

The Vibrio cholerae type VI secretion system can modulate host intestinal mechanics to displace gut bacterial symbionts

SL Logan, J Thomas, J Yan, RP Baker… - Proceedings of the …, 2018 - National Acad Sciences
Host-associated microbiota help defend against bacterial pathogens; however, the
mechanisms by which pathogens overcome this defense remain largely unknown. We …

Symbionts shape host innate immunity in honeybees

RD Horak, SP Leonard… - Proceedings of the …, 2020 - royalsocietypublishing.org
The gut microbiome plays a critical role in the health of many animals. Honeybees are no
exception, as they host a core microbiome that affects their nutrition and immune function …