The perception of nociceptive signals, which are translated into pain, plays a fundamental
role in the survival of organisms. Because pain is linked to a negative sensation, animals …

Injuries of various types occur commonly in the lives of humans and other animals and lead
to a pattern of persistent pain and recuperative behaviour that allows safe and effective …

Increased low frequency cortical oscillations are observed in people with neuropathic pain,
but the cause of such elevated cortical oscillations and their impact on pain development …

Activation of GABAA receptors on sensory axons produces a primary afferent depolarization
(PAD) that modulates sensory transmission in the spinal cord. While axoaxonic synaptic …

Presynaptic inhibition of primary afferent terminals is a powerful mechanism for controlling
sensory information flow into the spinal cord. Lamina I is the major spinal nociceptive …

Although spinal processing of sensory information greatly relies on afferent-driven (AD)
presynaptic inhibition (PI), our knowledge about how it shapes peripheral input to different …

In addition to the action potentials generated by the ongoing activation of single dorsal horn
neurons in the anesthetized cat, we often recorded small negative field potentials with a fast …

Previous studies from our laboratory showed that in the anesthetized cat, the intradermal
injection of capsaicin in the hindpaw facilitated the intraspinal field potentials (IFPs) evoked …

In the anesthetized cat the correlation between the ongoing cord dorsum potentials (CDPs)
recorded from different lumbar spinal segments has a non-random structure, suggesting …

A previous study has indicated that during the state of central sensitization induced by the
intradermic injection of capsaicin, there is a gradual facilitation of the dorsal horn neuronal …