[HTML][HTML] Simulation-based approaches for drug delivery systems: Navigating advancements, opportunities, and challenges

I Salahshoori, M Golriz, MAL Nobre, S Mahdavi… - Journal of Molecular …, 2024 - Elsevier
Efficient drug delivery systems (DDSs) play a pivotal role in ensuring pharmaceuticals'
targeted and effective administration. However, the intricate interplay between drug …

Application of Artificial Intelligence in Drug–Drug Interactions Prediction: A Review

Y Zhang, Z Deng, X Xu, Y Feng… - Journal of chemical …, 2023 - ACS Publications
Drug–drug interactions (DDI) are a critical aspect of drug research that can have adverse
effects on patients and can lead to serious consequences. Predicting these events …

Structure‐Based Drug Discovery with Deep Learning

R Özçelik, D van Tilborg, J Jiménez‐Luna… - …, 2023 - Wiley Online Library
Artificial intelligence (AI) in the form of deep learning has promise for drug discovery and
chemical biology, for example, to predict protein structure and molecular bioactivity, plan …

Omics-based deep learning approaches for lung cancer decision-making and therapeutics development

TO Tran, TH Vo, NQK Le - Briefings in Functional Genomics, 2024 - academic.oup.com
Lung cancer has been the most common and the leading cause of cancer deaths globally.
Besides clinicopathological observations and traditional molecular tests, the advent of …

Leveraging transformers‐based language models in proteome bioinformatics

NQK Le - Proteomics, 2023 - Wiley Online Library
In recent years, the rapid growth of biological data has increased interest in using
bioinformatics to analyze and interpret this data. Proteomics, which studies the structure …

Learning motif-based graphs for drug–drug interaction prediction via local–global self-attention

Y Zhong, G Li, J Yang, H Zheng, Y Yu… - Nature Machine …, 2024 - nature.com
Unexpected drug–drug interactions (DDIs) are important issues for both pharmaceutical
research and clinical applications due to the high risk of causing severe adverse drug …

Integrating Artificial Intelligence for Drug Discovery in the Context of Revolutionizing Drug Delivery

AI Visan, I Negut - Life, 2024 - mdpi.com
Drug development is expensive, time-consuming, and has a high failure rate. In recent
years, artificial intelligence (AI) has emerged as a transformative tool in drug discovery …

Explainable artificial intelligence for drug discovery and development-a comprehensive survey

R Alizadehsani, SS Oyelere, S Hussain… - IEEE …, 2024 - ieeexplore.ieee.org
The field of drug discovery has experienced a remarkable transformation with the advent of
artificial intelligence (AI) and machine learning (ML) technologies. However, as these AI and …

Explainability and white box in drug discovery

KK Kırboğa, S Abbasi… - Chemical Biology & Drug …, 2023 - Wiley Online Library
Recently, artificial intelligence (AI) techniques have been increasingly used to overcome the
challenges in drug discovery. Although traditional AI techniques generally have high …

Graph regularized probabilistic matrix factorization for drug-drug interactions prediction

S Jain, E Chouzenoux, K Kumar… - IEEE Journal of …, 2023 - ieeexplore.ieee.org
Co-administration of two or more drugs simultaneously can result in adverse drug reactions.
Identifying drug-drug interactions (DDIs) is necessary, especially for drug development and …