Recent drug design strategies and identification of key heterocyclic scaffolds for promising anticancer targets

A Mushtaq, P Wu, MM Naseer - Pharmacology & Therapeutics, 2024 - Elsevier
Cancer, a noncommunicable disease, is the leading cause of mortality worldwide and is
anticipated to rise by 75% in the next two decades, reaching approximately 25 million cases …

Synthesis, characterization and antifungal activity of imidazole chitosan derivatives

L Wu, L Fan, L Shi, C Wang, Z Pan, C Xu… - Carbohydrate Research, 2024 - Elsevier
Five novel imidazole-functionalized chitosan derivatives 3a-3e were synthesized via
addition reactions of chitosan with imidazole derivatives. The partial incorporation of …

[HTML][HTML] An Innovative Method of Improving an Extract of Andrographis paniculata from Leaves: Its Anticancer Effect Involves the Cell Endoplasmic Reticulum

J Maiuolo, R Caminiti, V Mazza, F Oppedisano… - International Journal of …, 2025 - mdpi.com
In this manuscript, the effects of two extracts from Andrographis paniculata were tested:(a)
an extract titrated to 49.7% of andrographolide and obtained from leaves of the plant:(b) the …

Experimental and Theoretical Studies for Noncovalent Interactions Analysis of 2-Phenyl Imidazole Derivative: Perspective for Anti-Inflammatory Activity

M Mishra, A Jaiswal, MD Mitra… - Polycyclic Aromatic …, 2024 - Taylor & Francis
Synthesis of 2-Phenyl imidazole derivative has been carried out for the studies of
quantitative non-covalent interactions and anti-inflammatory activity. Hirshfeld surface …