Global Dissemination of Carbapenemase-Producing Klebsiella pneumoniae: Epidemiology, Genetic Context, Treatment Options, and Detection Methods

CR Lee, JH Lee, KS Park, YB Kim, BC Jeong… - Frontiers in …, 2016 - frontiersin.org
The emergence of carbapenem-resistant Gram-negative pathogens poses a serious threat
to public health worldwide. In particular, the increasing prevalence of carbapenem-resistant …

Global dissemination of extensively drug‐resistant carbapenemase‐producing E nterobacteriaceae: clinical perspectives on detection, treatment and infection control

T Tängdén, CG Giske - Journal of internal medicine, 2015 - Wiley Online Library
The prevalence of carbapenem‐resistant Gram‐negative bacilli is on the rise worldwide,
posing a major public health threat. Previously, this was mostly a problem in Pseudomonas …

Understanding the epidemiology of multi-drug resistant gram-negative bacilli in the Middle East using a one health approach

I Dandachi, A Chaddad, J Hanna, J Matta… - Frontiers in …, 2019 - frontiersin.org
In the last decade, extended-spectrum cephalosporin and carbapenem resistant Gram-
negative bacilli (GNB) have been extensively reported in the literature as being …

Carbapenemase-producing Gram-negative bacteria: current epidemics, antimicrobial susceptibility and treatment options

SS Jean, WS Lee, C Lam, CW Hsu, RJ Chen… - Future …, 2015 - Taylor & Francis
Carbapenemases, with versatile hydrolytic capacity against β-lactams, are now an important
cause of resistance of Gram-negative bacteria. The genes encoding for the acquired …

Characterization of Carbapenem-Resistant Enterobacteriaceae with High Rate of Autochthonous Transmission in the Arabian Peninsula

A Sonnevend, AA Ghazawi, R Hashmey, W Jamal… - PloS one, 2015 - journals.plos.org
To establish the role of local transmission versus possible pathogen import due to previous
foreign exposure in infections caused by carbapenem non-susceptible Enterobacteriaceae …

Resistome of carbapenem- and colistin-resistant Klebsiella pneumoniae clinical isolates

S Lomonaco, MA Crawford, C Lascols, RE Timme… - PLoS …, 2018 - journals.plos.org
The emergence and dissemination of carbapenemases, bacterial enzymes able to inactivate
most β-lactam antibiotics, in Enterobacteriaceae is of increasing concern. The concurrent …

[HTML][HTML] Prevalence and molecular epidemiology of carbapenem-resistant Gram-negative bacilli and their resistance determinants in the Eastern Mediterranean …

A Sleiman, AG Abou Fayad, H Banna… - Journal of Global …, 2021 - Elsevier
Abstract Carbapenem resistance in Enterobacteriaceae, Acinetobacter baumannii, and
Pseudomonas aeruginosa is increasing worldwide, which led the WHO to list these bacteria …

Whole-genome assembly of Klebsiella pneumoniae coproducing NDM-1 and OXA-232 carbapenemases using single-molecule, real-time sequencing

Y Doi, TH Hazen, M Boitano, YC Tsai… - Antimicrobial agents …, 2014 - Am Soc Microbiol
The whole-genome sequence of a carbapenem-resistant Klebsiella pneumoniae strain,
PittNDM01, which coproduces NDM-1 and OXA-232 carbapenemases, was determined in …

Antimicrobial resistance among GLASS pathogens in conflict and non-conflict affected settings in the Middle East: a systematic review

C Truppa, MN Abo-Shehada - BMC infectious diseases, 2020 - Springer
Background In spite of the evident general negative effects of armed conflict on countries'
health systems and populations' health outcomes, little is known about similar impacts of …

Retrospective Analysis on Antimicrobial Resistance Trends and Prevalence of β-lactamases in Escherichia coli and ESKAPE Pathogens Isolated from Arabian …

M Nasser, S Palwe, RN Bhargava, MGJ Feuilloley… - Microorganisms, 2020 - mdpi.com
The production of diverse and extended spectrum β-lactamases among Escherichia coli and
ESKAPE pathogens is a growing threat to clinicians and public health. We aim to provide a …