Metal-based nanoparticle in cancer treatment: lessons learned and challenges

A Hheidari, J Mohammadi, M Ghodousi… - … in Bioengineering and …, 2024 - frontiersin.org
Cancer, being one of the deadliest diseases, poses significant challenges despite the
existence of traditional treatment approaches. This has led to a growing demand for …

Evaluation of sodium borocaptate (BSH) and boronophenylalanine (BPA) as boron delivery agents for neutron capture therapy (NCT) of cancer: an update and a …

RF Barth, N Gupta, S Kawabata - Cancer Communications, 2024 - Wiley Online Library
Boron neutron capture therapy (BNCT) is a cancer treatment modality based on the nuclear
capture and fission reactions that occur when boron‐10, a stable isotope, is irradiated with …

A small-molecule carrier for the intracellular delivery of a membrane-impermeable protein with retained bioactivity

X Ma, Z Zhang, A Barba-Bon, D Han, Z Qi, B Ge… - Proceedings of the …, 2024 - pnas.org
Intracellular protein delivery has the potential to revolutionize cell-biological research and
medicinal therapy, with broad applications in bioimaging, disease treatment, and genome …

In silico assessments of the small molecular boron agents to pave the way for artificial intelligence-based boron neutron capture therapy

Y Zhang, J Cai, NS Hosmane, Y Zhu - European Journal of Medicinal …, 2024 - Elsevier
Boron neutron capture therapy (BNCT) is a highly targeted, selective and effective technique
to cure various types of cancers, with less harm to the healthy cells. In principle, BNCT …

Diagnostic and theranostic technologies used in boron neutron capture therapy–A brief review

P Coghi, T Fazal, NS Hosmane, Y Zhu - Inorganic Chemistry …, 2024 - Elsevier
Boron neutron capture therapy (BNCT) is a highly targeted, selective and effective technique
to cure various types of cancers, with less harms to the healthy cells. In principle, BNCT …

Therapeutic potential of boron-based nanoparticles for enhanced glioblastoma treatment

DÇ Altındal - Journal of Drug Delivery Science and Technology, 2024 - Elsevier
Glioblastoma multiforme (GBM) is the most common type of brain tumor and its treatment is
difficult due to its infiltrative nature into normal brain tissue, heterogeneity, and presence of …

Metallacarboranes in Medicinal Chemistry: Current Advances and Future Perspectives

M Gos, J Cebula, TM Goszczyński - Journal of Medicinal …, 2024 - ACS Publications
Metallacarboranes, exemplified by cobalt bis (dicarbollide)([COSAN]−), have excelled their
historical metallocene analogue label to become promising in drug design, medical studies …

Synthesis of novel zwitterionic nido-carborane-containing derivatives of cysteine and methionine

AA Telegina, DA Gruzdev, MA Ezhikova… - Russian Chemical …, 2024 - Springer
Abstract Alkylation of 9-methylthio-nido-carborane under the action of the corresponding
iodo derivatives of alanine and homoalanine furnished new (nido-carboran-9-yl) derivatives …

[HTML][HTML] Boron neutron capture therapy of cancer: where do we stand now?

RF Barth, G Wu, HV Maria da Graca… - Cancer …, 2024 - pmc.ncbi.nlm.nih.gov
Boron neutron capture therapy of cancer: where do we stand now? - PMC Skip to main content
Here's how you know Official websites use .gov A .gov website belongs to an official government …

Boron-Containing Mesoporous Silica Nanoparticles with Effective Delivery and Targeting of Liver Cancer Cells for Boron Neutron Capture Therapy

H Tang, Z Wang, H Hao, W Luo, J Yang… - … Applied Materials & …, 2024 - ACS Publications
Nanocarriers have been researched comprehensively for the development of novel boron-
containing agents in boron neutron capture therapy (BNCT). We designed and synthesized …