Regioselectivity in the ring opening of non-activated aziridines

S Stanković, M D'hooghe, S Catak, H Eum… - Chemical Society …, 2012 - pubs.rsc.org
In this critical review, the ring opening of non-activated 2-substituted aziridinesvia
intermediate aziridinium salts will be dealt with. Emphasis will be put on the relationship …

Morpholines. Synthesis and biological activity

VA Pal'Chikov - Russian Journal of Organic Chemistry, 2013 - Springer
The review analyzes methods of synthesis of 1, 4-oxazines (morpholines) starting from
vicinal amino alcohols and their derivatives, oxiranes, and aziridines. Examples of using …

Regiospecific Alkene Aminofunctionalization via an Electrogenerated Dielectrophile

DE Holst, C Dorval, CK Winter, IA Guzei… - Journal of the …, 2023 - ACS Publications
Modular strategies to rapidly increase molecular complexity have proven immensely
synthetically valuable. In principle, transformation of an alkene into a dielectrophile presents …

Synthesis of 6- and 7-Membered N-Heterocycles Using α-Phenylvinylsulfonium Salts

JV Matlock, TD Svejstrup, P Songara… - Organic …, 2015 - ACS Publications
A concise synthesis of stereodefined C-substituted morpholines, piperazines, azepines, and
oxazepines in moderate to excellent yields (27% to 75%) is reported by reaction of 1, 2-or 1 …

Catalytic asymmetric synthesis of substituted morpholines and piperazines

H Zhai, A Borzenko, YY Lau, SH Ahn, LL Schafer - Angewandte Chemie, 2012 - infona.pl
Unter zwei Bedingungen: Die modulare und enantioselektive Synthese von 3‐substituierten
Morpholinen sowie die diastereoselektive Synthese von 2, 5‐substituierten Piperazinen wird …

Stereoselective synthesis of morpholines via copper-promoted oxyamination of alkenes

FC Sequeira, SR Chemler - Organic letters, 2012 - ACS Publications
A new copper (II) 2-ethylhexanoate-promoted addition of an alcohol and an amine across an
alkene (oxyamination) is reported. The alcohol addition is intramolecular, while coupling …

Desymmetrization of Cyclohexadienones via [3+ 2]/[2+ 1] Domino Annulation: Access to Cyclopropane Fused Tricyclic Enones

Y Zhu, S Wang, B Fang, Q Li, G Qi… - Advanced Synthesis & …, 2024 - Wiley Online Library
Abstract A [3+ 2]/[2+ 1] domino annulation reaction of cyclohexadienones and α‐aryl
vinylsulfonium salts has been reported. A range of cyclopropane fused tricyclic enones …

Recent developments in vinylsulfonium and vinylsulfoxonium salt chemistry

M Mondal, S Chen, NJ Kerrigan - Molecules, 2018 - mdpi.com
This review describes advances in the literature since 2000 in the area of reactions of
vinylsulfonium and vinylsulfoxonium salts, with a particular emphasis on stereoselective …

Synthesis of α-substituted vinylsulfonium salts and their application as annulation reagents in the formation of epoxide-and cyclopropane-fused heterocycles

JV Matlock, SP Fritz, SA Harrison, DM Coe… - The Journal of …, 2014 - ACS Publications
The discovery of new methods for the synthesis of classes of potentially bioactive molecules
remains an important goal for synthetic chemists. Vinylsulfonium salts have been used for …

An efficient synthesis of imidazolinium salts using vinyl sulfonium salts

EM McGarrigle, SP Fritz, L Favereau, M Yar… - Organic …, 2011 - ACS Publications
The synthesis of imidazolinium salts from the reaction of formamidines and (2-bromoethyl)
diphenylsulfonium triflate is described. A variety of symmetrical and unsymmetrical …