Abstract β-tricalcium phosphate (β-TCP) is one the most used and potent synthetic bone
graft substitute. It is not only osteoconductive, but also osteoinductive. These properties …

Rapid developments in Regenerative Medicine and Tissue Engineering has witnessed an
increasing drive toward clinical translation of breakthrough technologies. However, the …

Our populations are aging. Some experts predict that 30% of hospital beds will soon be
occupied by osteoporosis patients. Statistics show that 20% of patients suffering from an …

Autologous bone graft is considered as the gold standard in bone reconstructive surgery.
However, the quantity of bone available is limited and the harvesting procedure requires a …

Microporosity has a critical role in improving the osteogenesis of scaffolds for bone tissue
engineering. Although the exact mechanism, by which it promotes new bone formation, is …

Taking inspiration from nature, triply periodic minimal surfaces (TPMS) are tailored as a
promising tool for designing internal pore architecture of porous biomaterials. In the next …

Various types of grafts have been traditionally used to restore damaged bones. In the late
1960s, a strong interest was raised in studying ceramics as potential bone grafts due to their …

The regeneration of osteochondral tissue necessitates the re-establishment of a gradient
owing to the unique characteristics and healing potential of the chondral and osseous …

With the increasing demand for novel bone repair solutions that overcome the drawbacks of
current grafting techniques, the design of artificial bone scaffolds is a central focus in bone …

Large bone defects represent a significant challenge for clinicians and surgeons. Tissue
engineering for bone regeneration represents an innovative solution for this dilemma and …