Role of oxytocin in the control of stress and food intake

T Onaka, Y Takayanagi - Journal of neuroendocrinology, 2019 - Wiley Online Library
Oxytocin neurones in the hypothalamus are activated by stressful stimuli and food intake.
The oxytocin receptor is located in various brain regions, including the sensory information …

[HTML][HTML] The search for novel analgesics: targets and mechanisms

TL Yaksh, SA Woller, R Ramachandran… - F1000prime …, 2015 - ncbi.nlm.nih.gov
The management of the pain state is of great therapeutic relevance to virtually every medical
specialty. Failure to manage its expression has deleterious consequence to the well-being …

[HTML][HTML] A new population of parvocellular oxytocin neurons controlling magnocellular neuron activity and inflammatory pain processing

M Eliava, M Melchior, HS Knobloch-Bollmann, J Wahis… - Neuron, 2016 - cell.com
Oxytocin (OT) is a neuropeptide elaborated by the hypothalamic paraventricular (PVN) and
supraoptic (SON) nuclei. Magnocellular OT neurons of these nuclei innervate numerous …

Oxytocin modulates nociception as an agonist of pain-sensing TRPV1

Y Nersesyan, L Demirkhanyan, D Cabezas-Bratesco… - Cell reports, 2017 - cell.com
Oxytocin is a hormone with various actions. Oxytocin-containing parvocellular neurons
project to the brainstem and spinal cord. Oxytocin release from these neurons suppresses …

Oxytocin release increases with age and is associated with life satisfaction and prosocial behaviors

PJ Zak, B Curry, T Owen, JA Barraza - Frontiers in behavioral …, 2022 - frontiersin.org
Helping behaviors and life satisfaction generally increase after middle-age. Identifying the
neural substrates of prosocial behaviors in older adults may offer additional insights into …

The rostral agranular insular cortex, a new site of oxytocin to induce antinociception

M Gamal-Eltrabily… - Journal of …, 2020 - Soc Neuroscience
The rostral agranular insular cortex (RAIC) is a relevant structure in nociception. Indeed,
recruitment of GABAergic activity in RAIC promotes the disinhibition of the locus ceruleus …

Investigating the influence of social support on experimental pain and related physiological arousal: A systematic review and meta-analysis

X Che, R Cash, S Chung, PB Fitzgerald… - Neuroscience & …, 2018 - Elsevier
Social support is demonstrated to have mixed effects on both pain and related physiological
arousal. In this study, a meta-analysis was conducted to characterise these effects. A total of …

A novel role of oxytocin: Oxytocin-induced well-being in humans

E Ito, R Shima, T Yoshioka - Biophysics and physicobiology, 2019 - jstage.jst.go.jp
We review the involvement of a small molecule, oxytocin, in various effects of physical
stimulation of somatosensory organs, mindfulness meditation, emotion and fragrance on …

Up‐regulation of oxytocin receptors on peripheral sensory neurons mediates analgesia in chemotherapy‐induced neuropathic pain

L Li, P Li, J Guo, Y Wu, Q Zeng, N Li… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Chemotherapy‐induced neuropathic pain (CINP) currently has
limited effective treatment. Although the roles of oxytocin (OXT) and the oxytocin receptor …

Peripheral oxytocin receptors inhibit the nociceptive input signal to spinal dorsal horn wide-dynamic-range neurons

A González-Hernández, A Manzano-García… - Pain, 2017 - journals.lww.com
Oxytocin (OT) has emerged as a mediator of endogenous analgesia in behavioral and
electrophysiological experiments. In fact, OT receptors (OTRs) in the spinal dorsal horn …