Context.—There have been major advances in the understanding of melanoma since the
last revision of the World Health Organization (WHO) classification in 2006. Objective.—To …

Acral lentiginous melanoma is a histological subtype of cutaneous melanoma that occurs in
the glabrous skin of the palms, soles and the nail unit. Although in some countries …

Acral lentiginous melanoma is a distinct subtype of melanoma on acral skin. Patient
presentation at later stages and delayed diagnosis by physicians contribute to a worse …

Targeted therapies revolutionized the management of patients with advanced and
metastatic cutaneous melanoma. However, despite recent advances in the understanding of …

Acral melanoma commonly occurs in areas that are not exposed to much sunlight, such as
the sole of the foot. Little is known about risk factors and mutational processes of plantar …

Although there is a higher incidence of melanoma among non-Hispanic White individuals,
melanoma is diagnosed at more advanced stages and associated with worse survival rates …

Abstract In comparison to Non-Hispanic White individuals, cutaneous melanoma is far less
common in skin of color (SOC) patients but carries a poorer prognosis. Melanomas in SOC …

Background The clinicopathological and survival profiles across primary sites in acral
melanoma (AM) are still controversial and unclear. Methods This is a multi-center …

Acral melanomas arise on the non-hair bearing skin of the palms, soles and in the nail beds.
These rare tumors comprise 2–3% of all melanomas, are not linked to UV-exposure, and …

Background Acral melanoma (AM) is the most common histopathological subtype of
malignant melanoma in Asians. However, differences in the mutational profiles underlying …