Benzothiazines are one of the significant nitrogen containing heterocyclic scaffolds which
are found to be multipurpose in the fields of drug discovery and medicinal chemistry. They …

In the present study, a novel phosphoramide (L) and corresponding phosphoramide-
functionalized graphene oxide (GO-L) were synthesized. L was characterized by FT-IR, 1 H …

In this work, 22 new compounds were obtained and evaluated for their cytotoxic activity on
peripheral blood mononuclear cells (PBMC) and eight different tumor cell lines. All …

Human carbonic anhydrase IX (hCA IX) is a promising target for the development of
potential anticancer agents. In the current study, pharmacophore and 3D-QSAR models …

Background: Human Galectin-1, a protein of lectin family showing affinity towards β-
galactosides has emerged as a critical regulator of tumor progression and metastasis, by …

Azolyl benzothiazine carboxamides were prepared from benzothiazine carboxylate and
azolyl amines in the presence of NaOMe under ultrasonication. 4 …

This research reports a novel method for synthesizing new thiazole thioglycosides. This
series of thiazole thioglycosides were designed by the reaction of potassium …

A new, straightforward and eco-compatible route to C-(hetero) aryl nucleosides is reported.
This ribosylation process consists of a one-step FeCl3 catalyzed Friedel–Crafts β-C …

Three novel tiazofurin analogues having d-arabino stereochemistry and nitrogen
functionalities at the C-2′ position (5–7) have been designed and synthesized in multistep …

A new class of benzazolyl azolyl urea derivatives were prepared by the reaction of methyl
benzazoyl carbamates with azolyl amines in the presence of mild base potassium tert …