As failure rates for traditional antimicrobial therapies escalate, recent focus has shifted to
evolution-based therapies to slow resistance. Collateral sensitivity–the increased …

Background Antimicrobial resistance is a major healthcare burden, aggravated when it
extends to multiple drugs. While cross-resistance is well-studied experimentally, it is not the …

Background and objectives Antimicrobial resistance is a major healthcare burden,
aggravated when it extends to multiple drugs. While cross-resistance is well-studied …

Saavutettavan opinnäytetyön ohje Page 1 Assessing the likelihood of wastewater treatment
plant acting as a hotspot for development of antimicrobial resistance Ossi Kasurinen Master …

Antibiotics are used to treat bacterial infections, as they can kill or inhibit the growth of
bacterial populations. However, the misuse of antibiotics may also promote the evolution of …

Invading bacterial pathogens are confronted by numerous challenges including harsh
environmental conditions at the site of infection, host immune responses and exposure to …

Collateral sensitivity (CS) occurs when bacteria develop resistance to one antibiotic leading
to an increase in antibiotic sensitivity towards a second antibiotic. The phenomenon of CS …

Statistical learning for complex data to enable precision medicine strategies Statistical learning
for complex data to enable precision medicine strategies Zwep, LB Citation Zwep, LB (2023, pril …