One of the most unique physical features of cell adhesion to external surfaces is the active
generation of mechanical force at the cell-material interface. This includes pulling forces …

Plasma membrane curvature is an important factor in the regulation of cellular phenotype
and is critical for various cellular activities including the shedding of extracellular vesicles …

Diffusion-weighted MRI (DWI) is a sensitive and reliable marker of cerebral ischemia. Within
minutes of an ischemic event in the brain, the microscopic motion of water molecules …

In eukaryotic cells, small changes in cell volume can serve as important signals for cell
proliferation, death, and migration. Volume and shape regulation also directly impacts the …

Axons are ultrathin membrane cables that are specialized for the conduction of action
potentials. Although their diameter is variable along their length, how their morphology is …

Due to surface tension, a beading instability takes place in a long enough fluid column that
results in the breakup of the column and the formation of smaller packets with the same …

Asymmetric cell division is common in biology and plays critical roles in differentiation and
development. Unicellular organisms are often used as model systems for understanding the …

Our bodies are in constant motion and so are the neurons that invade each tissue. Motion-
induced neuron deformation and damage are associated with several neurodegenerative …

Blast-induced traumatic brain injury (TBI) has become a signature wound of recent military
activities and is the leading cause of death and long-term disability among US soldiers. The …

Neuronal axons must navigate a mechanically heterogeneous environment to reach their
targets, but the biophysical mechanisms coupling mechanosensation, growth, and …