Brain transcriptome-wide association study implicates novel risk genes underlying schizophrenia risk

C Zhang, X Li, L Zhao, W Guo, W Deng… - Psychological …, 2023 - cambridge.org
BackgroundTo identify risk genes whose expression are regulated by the reported risk
variants and to explore the potential regulatory mechanism in schizophrenia (SCZ) …

Association of retinal nerve fiber abnormalities with serum CNTF and cognitive functions in schizophrenia patients

Y Liu, L Huang, Y Tong, J Chen, D Gao, F Yang - PeerJ, 2020 - peerj.com
Background Recent studies have reported reductions in retinal nerve fiber layers (RNFL) in
schizophrenia. Ciliary neurotrophic factor (CNTF) has shown protective effects on both the …

Gray matter structural alterations of cortico-striato-thalamo-cortical loop in familial Paroxysmal Kinesigenic Dyskinesia

D Wang, H Jin, F Xie, Z Wang, W Xing - Heliyon, 2024 - cell.com
Background Previous studies have indicated that patients with Paroxysmal Kinesigenic
Dyskinesia (PKD) exhibit reduced gray matter volume in certain brain regions within the …

Single exposure to cocaine impairs reinforcement learning by potentiating the activity of neurons in the direct striatal pathway in mice

Z Diao, Y Di, M Wu, C Zhai, M Kang, Y Li, Y Liu… - Neuroscience …, 2021 - Springer
Plasticity in the glutamatergic synapses on striatal medium spiny neurons (MSNs) is not only
essential for behavioral adaptation but also extremely vulnerable to drugs of abuse …

Effects of icariin on NRG1-ErbB signaling pathways in hippocampus of schizophrenia rats

Y Liu, L Lin, W Xiao, Q Ji, Y Liu - Chinese Journal of Tissue Engineering …, 2023 - cjter.com
BACKGROUND: Icariin is one of the effective active components of Epimedium, which is
important for reinforcing kidney and strengthening yang. It can not only promote the function …

Erbb4 deletion from fast-spiking interneurons causes psychosis-relevant neuroimaging phenotypes

A Kiemes, ME Serrano Navacerrada, E Kim, K Randall… - bioRxiv, 2022 - biorxiv.org
Converging lines of evidence suggest that dysfunction of cortical parvalbumin-expressing
(PV+) GABAergic interneurons is a core feature of psychosis. This dysfunction is thought to …

淫羊藿苷对精神分裂症模型大鼠认知及海马组织NRG1/ErbB 信号通路的影响

刘运琴, 林丽, 肖文昊, 戢秋明, 刘燕芹 - 中国组织工程研究, 2023 - cjter.com
淫羊藿苷对精神分裂症模型大鼠认知及海马组织NRG1/ErbB 信号通路的影响 Page 1 3236|中国
组织工程研究|第27卷|第20期|2023年7月 中国组织工程研究 Chinese Journal of Tissue …

Erbb4 Deletion From Inhibitory Interneurons Causes Psychosis-Relevant Neuroimaging Phenotypes

A Kiemes, ME Serrano Navacerrada, E Kim… - Schizophrenia …, 2023 - academic.oup.com
Abstract Background and Hypothesis Converging lines of evidence suggest that dysfunction
of cortical GABAergic inhibitory interneurons is a core feature of psychosis. This dysfunction …

Association between ErbB4 gene function in synaptogenesis and schizophrenia pathogenesis

R Li, M Chen, H Tian, G Li, L Wang, W Tu… - Biotechnology & …, 2020 - Taylor & Francis
This study investigated the role of ErbB4, the schizophrenia susceptibility gene, in
synaptogenesis and synaptic transmission and its association with the pathogenesis of …

A Review of Structural Abnormality in Schizophrenia

K Xuan - 2021 International Conference on Public Art and …, 2022 - atlantis-press.com
Over the past 20 years, the understanding of schizophrenia has deepened. As a brain
disease, schizophrenia has profoundly affected generations. It is a chronic brain disorder …