Phagocytes are key cellular participants determining important aspects of host exposure to
nanomaterials, initiating clearance, biodistribution and the tenuous balance between host …

As direct effector cells for osteogenesis, osteoblastic cells are commonly used for evaluating
the in vitro osteogenic capacity of bone biomaterials, and the traditional biological principle …

The regulatory functions of the immune response in tissue healing, repair, and regeneration
have been evidenced in the last decade. Immune cells play central roles in immune …

Tissue engineering strategies for treating bone loss to date have largely focused on
targeting stem cells or vascularization. Immune cells, including macrophages and T cells …

Synthetic calcium phosphate (CaP) ceramics represent the most widely used biomaterials
for bone regenerative treatments due to their biological performance that is characterized by …

Abstract The role of Bone Tissue Engineering in the field of Regenerative Medicine has
been the topic of substantial research over the past two decades. Technological advances …

Tissue repair/regeneration, after implantation or injury, involves comprehensive
physiological processes wherein immune responses play a crucial role to enable tissue …

The regulatory role of the immune system in maintaining bone homeostasis and restoring its
functionality, when disturbed due to trauma or injury, has become evident in recent years …

Calcium phosphate is applied in many products in biomedicine, but also in toothpastes and
cosmetics. In some cases, it is present in nanoparticulate form, either on purpose or after …

Impaired bone healing occurs in 5–10% of cases following injury, leading to a significant
economic and clinical impact. While an inflammatory response upon injury is necessary to …