Thrombotic thrombocytopenic purpura: pathophysiology, diagnosis, and management

S Sukumar, B Lämmle, SR Cataland - Journal of clinical medicine, 2021 - mdpi.com
Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy
characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and …

Thrombotic thrombocytopenic purpura

JA Kremer Hovinga, P Coppo, B Lämmle… - Nature reviews Disease …, 2017 - nature.com
Thrombotic thrombocytopenic purpura (TTP; also known as Moschcowitz disease) is
characterized by the concomitant occurrence of often severe thrombocytopenia …

Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies.

M Scully, BJ Hunt, S Benjamin… - British journal of …, 2012 - search.ebscohost.com
The article focuses on providing guidelines to healthcare professionals for the diagnosis of
various types and sub groups of Thrombotic thrombocytopenic purpura (TTP), occurring …

Thrombotic thrombocytopenic purpura

BS Joly, P Coppo, A Veyradier - Blood, The Journal of the …, 2017 - ashpublications.org
Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening thrombotic
microangiopathy characterized by microangiopathic hemolytic anemia, severe …

Pathophysiology of thrombotic thrombocytopenic purpura

JE Sadler - Blood, The Journal of the American Society of …, 2017 - ashpublications.org
The discovery of a disintegrin-like and metalloproteinase with thrombospondin type 1 motif,
member 13 (ADAMTS13) revolutionized our approach to thrombotic thrombocytopenic …

Survival and relapse in patients with thrombotic thrombocytopenic purpura

JAK Hovinga, SK Vesely, DR Terrell… - Blood, The Journal …, 2010 - ashpublications.org
Survival of patients with thrombotic thrombocytopenic purpura (TTP) improved dramatically
with plasma exchange treatment, revealing risk for relapse. The Oklahoma TTP Registry is a …

Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies

J Zuber, F Fakhouri, LT Roumenina, C Loirat… - Nature Reviews …, 2012 - nature.com
In the past decade, a large body of evidence has accumulated in support of the critical role
of dysregulation of the alternative complement pathway in atypical haemolytic uraemic …

Predictive features of severe acquired ADAMTS13 deficiency in idiopathic thrombotic microangiopathies: the French TMA reference center experience

P Coppo, M Schwarzinger, M Buffet, A Wynckel… - PloS one, 2010 - journals.plos.org
Severe ADAMTS13 deficiency occurs in 13% to 75% of thrombotic microangiopathies
(TMA). In this context, the early identification of a severe, antibody-mediated, ADAMTS13 …

Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura

JE Sadler - Blood, The Journal of the American Society of …, 2008 - ashpublications.org
Discoveries during the past decade have revolutionized our understanding of idiopathic
thrombotic thrombocytopenic purpura (TTP). Most cases in adults are caused by acquired …

Regional UK TTP registry: correlation with laboratory ADAMTS 13 analysis and clinical features

M Scully, H Yarranton, R Liesner… - British journal of …, 2008 - Wiley Online Library
Thrombotic thrombocytopenic purpura (TTP) is an acute, rare, life‐threatening disorder. This
report presents the South East (SE) England registry for TTP, from April 2002 to December …