Clinical neurocardiology defining the value of neuroscience‐based cardiovascular therapeutics

K Shivkumar, OA Ajijola, I Anand… - The Journal of …, 2016 - Wiley Online Library
The autonomic nervous system regulates all aspects of normal cardiac function, and is
recognized to play a critical role in the pathophysiology of many cardiovascular diseases. As …

Vagus nerve stimulation: Surgical technique of implantation and revision and related morbidity

F Giordano, A Zicca, C Barba, R Guerrini, L Genitori - Epilepsia, 2017 - Wiley Online Library
Indications for vagus nerve stimulation (VNS) therapy include focal, multifocal epilepsy, drop
attacks (tonic/atonic seizures), Lennox‐Gastaut syndrome, tuberous sclerosis complex …

A wireless millimetre-scale implantable neural stimulator with ultrasonically powered bidirectional communication

DK Piech, BC Johnson, K Shen, MM Ghanbari… - Nature biomedical …, 2020 - nature.com
Clinically approved neural stimulators are limited by battery requirements, as well as by their
large size compared with the stimulation targets. Here, we describe a wireless, leadless and …

Non-invasive vagus nerve stimulation in healthy humans reduces sympathetic nerve activity

JA Clancy, DA Mary, KK Witte, JP Greenwood… - Brain stimulation, 2014 - Elsevier
Background Vagus nerve stimulation (VNS) is currently used to treat refractory epilepsy and
is being investigated as a potential therapy for a range of conditions, including heart failure …

Complications and safety of vagus nerve stimulation: 25 years of experience at a single center

D Révész, B Rydenhag, E Ben-Menachem - Journal of Neurosurgery …, 2016 - thejns.org
OBJECTIVE The goal of this paper was to investigate surgical and hardware complications
in a longitudinal retrospective study. METHODS The authors of this registry study analyzed …

The effect of transcutaneous vagus nerve stimulation on pain perception–an experimental study

V Busch, F Zeman, A Heckel, F Menne, J Ellrich… - Brain stimulation, 2013 - Elsevier
BACKGROUND: Recent preclinical work strongly suggests that vagus nerve stimulation
efficiently modulates nociception and pain processing in humans. Most recently, a medical …

Non-invasive vagus nerve stimulation acutely improves spontaneous cardiac baroreflex sensitivity in healthy young men: a randomized placebo-controlled trial

D Antonino, AL Teixeira, PM Maia-Lopes, MC Souza… - Brain stimulation, 2017 - Elsevier
Background Despite positive outcomes of transcutaneous vagus nerve stimulation (tVNS)
via the auricular branch of the vagus nerve (ABVN), the mechanisms underlying these …

Transcutaneous auricular vagus nerve stimulation

J Ellrich - Journal of Clinical Neurophysiology, 2019 - journals.lww.com
Invasive vagus nerve stimulation (VNS) is an approved treatment for drug-resistant epilepsy.
Besides recognized clinical efficacy in about 60% of patients, there are major drawbacks …

Autonomic modulation of cardiac arrhythmias: methods to assess treatment and outcomes

S Stavrakis, K Kulkarni, JP Singh, DG Katritsis… - Clinical …, 2020 - jacc.org
The autonomic nervous system plays a central role in the pathogenesis of multiple cardiac
arrhythmias, including atrial fibrillation and ventricular tachycardia. As such, autonomic …

[HTML][HTML] Complications of vagal nerve stimulation for drug-resistant epilepsy: a single center longitudinal study of 143 patients

H Kahlow, M Olivecrona - Seizure, 2013 - Elsevier
Purpose To longitudinally study surgical and hardware complications to vagal nerve
stimulation (VNS) treatment in patients with drug-resistant epilepsy. Methods In a …