DExH/D-box helicases at the frontline of intrinsic and innate immunity against viral infections
B Bonaventure, C Goujon - Journal of General Virology, 2022 - microbiologyresearch.org
DExH/D-box helicases are essential nucleic acid and ribonucleoprotein remodelers
involved in all aspects of nucleic acid metabolism including replication, gene expression …
involved in all aspects of nucleic acid metabolism including replication, gene expression …
RNA splicing as a biomarker and phenotypic driver of meningioma DNA-methylation groups
Background Advances in our understanding of the molecular biology of meningiomas have
led to significant gains in the ability to predict patient prognosis and tumor recurrence and to …
led to significant gains in the ability to predict patient prognosis and tumor recurrence and to …
Ecdysoneless protein regulates viral and cellular mRNA splicing to promote cervical oncogenesis
High-risk human papillomaviruses (HPV), exemplified by HPV16/18, are causally linked to
human cancers of the anogenital tract, skin, and upper aerodigestive tract. Previously, we …
human cancers of the anogenital tract, skin, and upper aerodigestive tract. Previously, we …
Xrp1 governs the stress response program to spliceosome dysfunction
D Stanković, LS Tain, M Uhlirova - Nucleic Acids Research, 2024 - academic.oup.com
Co-transcriptional processing of nascent pre-mRNAs by the spliceosome is vital to
regulating gene expression and maintaining genome integrity. Here, we show that the …
regulating gene expression and maintaining genome integrity. Here, we show that the …
ECD functions as a novel RNA-binding protein to regulate mRNA splicing
M Raza, AR Rajan, A Kalluchi, I Saleem, BB Kennedy… - bioRxiv, 2025 - biorxiv.org
The human ecdysoneless protein (ECD) plays an essential role in the regulation of cell cycle
and cell survival. ECD has been implicated in RNA splicing through its association with the …
and cell survival. ECD has been implicated in RNA splicing through its association with the …
Molecular Signature Expands the Landscape of Driver Negative Thyroid Cancers
LV Bim, TNR Carneiro, VC Buzatto, GA Colozza-Gama… - Cancers, 2021 - mdpi.com
Simple Summary Thyroid cancer is the most common endocrine malignancy. However, the
cytological diagnosis of certain malignant thyroid tumors and their benign counterparts is a …
cytological diagnosis of certain malignant thyroid tumors and their benign counterparts is a …
Ecdysoneless overexpression drives mammary tumorigenesis through upregulation of c-MYC and glucose metabolism
Ecdysoneless (ECD) protein is essential for embryogenesis, cell-cycle progression, and
cellular stress mitigation with an emerging role in mRNA biogenesis. We have previously …
cellular stress mitigation with an emerging role in mRNA biogenesis. We have previously …