Thirty years ago, John French wrote a seminal review describing the unique properties of
the arterial intima. 1 His major point was that the smooth muscle cells of the intima have a …

In the current vascular interventional environment, high restenosis rates have increased
awareness of the significance of intimal hyperplasia, a chronic structural lesion that …

Granulation tissue fibroblasts (myofibroblasts) develop several ultrastructural and
biochemical features of smooth muscle (SM) cells, including the presence of microfilament …

The cellular composition of human atherosclerotic plaques was analyzed by immunologic
techniques. Plaques were removed from the internal carotid artery during surgery, and a …

A monoclonal antibody (anti-alpha sm-1) recognizing exclusively alpha-smooth muscle actin
was selected and characterized after immunization of BALB/c mice with the NH2-terminal …

'Provides comprehensive detail on the various aspects of particular molecules involved in
the phases of injury and repair and the cellular movements and processes.... This is an …

Background The adventitia undergoes remodeling changes after a deep medial coronary
injury. Because this process is associated with the formation of adventitial myofibroblasts …

Granulation tissue fibroblasts (myofibroblasts) develop several ultrastructural and
biochemical features of smooth muscle (SM) cells, including the presence of microfilament …

Smooth muscle proliferation has been recognized as central to the pathology of both major
forms of vascular disease: atherosclerosis and hypertension. Recent advances in our …

▪ Abstract In many organs and tissues, the cellular response to injury is associated with a
reiteration of specific developmental processes. Studies have shown that, in response to …