The extracellular matrix (ECM) plays a crucial role in all parts of the eye, from maintaining
clarity and hydration of the cornea and vitreous to regulating angiogenesis, intraocular …

Subretinal fibrosis is a result of a wound healing response that follows choroidal
neovascularization in neovascular age-related macular degeneration (nAMD). Although anti …

Background Diabetic retinopathy is a major complication of diabetes mellitus, where in its
most advanced form ischemic changes lead to the development of retinal …

Anti-vascular endothelial growth factor (anti-VEGF) crunch syndrome describes the
progression to tractional retinal detachment following intravitreal anti-VEGF therapy in an …

Twenty-five percent of diabetes-related vision loss stems from complications of proliferative
diabetic retinopathy (PDR). Panretinal photocoagulation has been the preferred treatment of …

Background Postoperative vitreous cavity haemorrhage (POVCH) is a significant
complication following vitrectomy for proliferative diabetic retinopathy (PDR). It delays visual …

Placental growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF)
family. Upon binding to VEGF-and neuropilin-receptor sub-types, PlGF modulates a range of …

Purpose: To systematically review and perform meta-analysis on the available randomized
controlled trial data for anti-vascular endothelial growth factor (anti-VEGF) agents in the …

Abstract The Early Treatment Diabetic Retinopathy Study (ETDRS) and other standardized
classification schemes have laid a foundation for tremendous advances in the …

Background/aims To evaluate the efficacy of antivascular endothelial growth factor (anti-
VEGF) agents pretreatment before vitrectomy for patients with complicated proliferative …