[HTML][HTML] Effects of apigenin on gastric cancer cells

A Pratas, B Malhão, R Palma, P Mendonça… - Biomedicine & …, 2024 - Elsevier
Gastric Cancer (GC) is one of the most prevalent cancers worldwide. As the currently
available therapeutic options are invasive, new and more benign options are being …

Unveiling novel avenues in mtor-targeted therapeutics: Advancements in glioblastoma treatment

S Singh, D Barik, K Lawrie, I Mohapatra… - International journal of …, 2023 - mdpi.com
The mTOR signaling pathway plays a pivotal and intricate role in the pathogenesis of
glioblastoma, driving tumorigenesis and proliferation. Mutations or deletions in the PTEN …

Highly-efficient gallium-interference tumor therapy mediated by gallium-enriched prussian blue nanomedicine

J Yao, Y Qiu, J Xing, Z Li, A Zhang, K Tu, M Peng… - ACS …, 2024 - ACS Publications
Prussian blue (PB)-based nanomedicines constructed from metal ion coordination remain
restricted due to their limited therapeutic properties, and their manifold evaluation complexity …

Transgenerational hormesis in healthy aging and antiaging medicine from bench to clinics: role of food components

V Calabrese, N Osakabe, R Siracusa… - Mechanisms of Ageing …, 2024 - Elsevier
Neurodegenerative diseases have multifactorial pathogenesis, mainly involving
neuroinflammatory processes. Finding drugs able to treat these diseases, expecially …

CCR5 and Inflammatory Storm

Y Lin, S Liu, Y Sun, C Chen, S Yang, G Pei, M Lin… - Ageing Research …, 2024 - Elsevier
Chemokines and their corresponding receptors play crucial roles in orchestrating
inflammatory and immune responses, particularly in the context of pathological conditions …

Dysregulation of autophagy in gastric carcinoma: Pathways to tumor progression and resistance to therapy

W Wen, YN Ertas, A Erdem, Y Zhang - Cancer Letters, 2024 - Elsevier
The considerable death rates and lack of symptoms in early stages of gastric cancer (GC)
make it a major health problem worldwide. One of the most prominent risk factors is infection …

[HTML][HTML] MODY Only Monogenic? A Narrative Review of the Novel Rare and Low-Penetrant Variants

I Hasballa, D Maggi - International Journal of Molecular Sciences, 2024 - mdpi.com
Maturity-onset diabetes of the young (MODY) represents the most frequent form of
monogenic diabetes mellitus (DM), currently classified in 14 distinct subtypes according to …

Vistusertib improves pulmonary inflammation and fibrosis by modulating inflammatory/oxidative stress mediators via suppressing the mTOR signalling

TB Shaikh, Y Chandra, SB Andugulapati… - Inflammation Research, 2024 - Springer
Introduction Inflammation and oxidative stress are key factors in the development of
pulmonary fibrosis (PF) by promoting the differentiation of fibroblasts through modulating …

Communication molecules (ncRNAs) mediate tumor-associated macrophage polarization and tumor progression

M Yao, X Mao, Z Zhang, F Cui, S Shao… - Frontiers in Cell and …, 2024 - frontiersin.org
Non-coding RNAs play important roles in tumor cells and macrophages and participate in
their communication as messengers. Non-coding RNAs have an impact in tumor cell …

Transcriptome-based network analysis reveals hub immune genes and pathways of hepatopancreas against LPS in Amphioctopus fangsiao

Z Li, J Gu, X Huang, Z Lu, Y Feng, X Xu… - Fish & Shellfish …, 2024 - Elsevier
The hepatopancreas is the biggest digestive organ in Amphioctopus fangsiao (A. fangsiao),
but also undertakes critical functions like detoxification and immune defense. Generally …