Left ventricular hypertrophy and sudden cardiac death

G Giamouzis, A Dimos, A Xanthopoulos… - Heart Failure …, 2022 - Springer
Sudden cardiac death (SCD) is among the leading causes of death worldwide, and it
remains a public health problem, as it involves young subjects. Current guideline-directed …

Advances in heart regeneration based on cardiomyocyte proliferation and regenerative potential of binucleated cardiomyocytes and polyploidization

M Leone, FB Engel - Clinical Science, 2019 - portlandpress.com
One great achievement in medical practice is the reduction in acute mortality of myocardial
infarction due to identifying risk factors, antiplatelet therapy, optimized hospitalization and …

Long noncoding RNA Chast promotes cardiac remodeling

J Viereck, R Kumarswamy, A Foinquinos… - Science translational …, 2016 - science.org
Recent studies highlighted long noncoding RNAs (lncRNAs) to play an important role in
cardiac development. However, understanding of lncRNAs in cardiac diseases is still …

Novel insights into the athlete's heart: is myocardial work the new champion of systolic function?

M Tokodi, A Oláh, A Fábián, BK Lakatos… - European Heart …, 2022 - academic.oup.com
Aims We sought to investigate the correlation between speckle-tracking echocardiography
(STE)-derived myocardial work (MW) and invasively measured contractility in a rat model of …

[HTML][HTML] Longitudinal strain reflects ventriculoarterial coupling rather than mere contractility in rat models of hemodynamic overload–induced heart failure

M Ruppert, BK Lakatos, S Braun, M Tokodi… - Journal of the American …, 2020 - Elsevier
Background Longitudinal strain (LS) is a sensitive marker of systolic function. Recent
findings suggest that both myocardial contractility and loading conditions determine LS. The …

[HTML][HTML] Characterization of the dynamic changes in left ventricular morphology and function induced by exercise training and detraining

A Oláh, A Kovács, Á Lux, M Tokodi, S Braun… - International Journal of …, 2019 - Elsevier
Background Although exercise-induced cardiac hypertrophy has been intensively
investigated, its development and regression dynamics have not been comprehensively …

[HTML][HTML] Sex differences in morphological and functional aspects of exercise-induced cardiac hypertrophy in a rat model

A Oláh, C Mátyás, D Kellermayer, M Ruppert… - Frontiers in …, 2019 - frontiersin.org
Background: Recent evidences suggest that sex hormones may be involved in the
regulation of exercise-induced left ventricular (LV) hypertrophy. However, the sex-specific …

Allicin improves the function of cardiac microvascular endothelial cells by increasing PECAM-1 in rats with cardiac hypertrophy

P Shi, Y Cao, J Gao, B Fu, J Ren, L Ba, C Song, H Qi… - Phytomedicine, 2018 - Elsevier
Objective Cardiac microvascular damage is significantly associated with the development of
cardiac hypertrophy (CH). Researchers found that allicin could inhibit CH, but the …

Ablation of the N terminus of cardiac essential light chain promotes the super‐relaxed state of myosin and counteracts hypercontractility in hypertrophic …

YH Sitbon, K Kazmierczak, J Liang, S Yadav… - The FEBS …, 2020 - Wiley Online Library
In this study, we focus on the molecular mechanisms associated with the A57G (Ala57‐to‐
Gly57) mutation in myosin essential light chains (ELCs), found to cause hypertrophic …

Influence of high-intensity interval training and intermittent fasting on myocardium apoptosis pathway and cardiac morphology of healthy rats

MR Carvalho, MLM Mendonça, JML Oliveira… - Life Sciences, 2021 - Elsevier
Aim To evaluate the influence of intermittent fasting and high-intensity interval training (HIIT)
on myocardial apoptosis signaling and cardiac morphological characteristics in healthy rats …