Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments

SN Lone, S Nisar, T Masoodi, M Singh, A Rizwan… - Molecular cancer, 2022 - Springer
Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly
being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have …

Liquid biopsy: from discovery to clinical application

C Alix-Panabières, K Pantel - Cancer discovery, 2021 - AACR
Over the past 10 years, circulating tumor cells (CTC) and circulating tumor DNA (ctDNA)
have received enormous attention as new biomarkers and subjects of translational research …

Liquid biopsy and minimal residual disease—latest advances and implications for cure

K Pantel, C Alix-Panabières - Nature Reviews Clinical Oncology, 2019 - nature.com
Liquid biopsy has been introduced as a new diagnostic concept predicated on the analysis
of circulating tumour cells (CTCs) or circulating tumour-derived factors, in particular, cell-free …

Liquid biopsy of cancer: a multimodal diagnostic tool in clinical oncology

R Palmirotta, D Lovero, P Cafforio… - … in medical oncology, 2018 - journals.sagepub.com
Over the last decades, the concept of precision medicine has dramatically renewed the field
of medical oncology; the introduction of patient-tailored therapies has significantly improved …

Clinical applications of circulating tumor cells and circulating tumor DNA as liquid biopsy

C Alix-Panabières, K Pantel - Cancer discovery, 2016 - AACR
Abstract “Liquid biopsy” focusing on the analysis of circulating tumor cells (CTC) and
circulating cell-free tumor DNA (ctDNA) in the blood of patients with cancer has received …

[HTML][HTML] Liquid biopsies, what we do not know (yet)

A Bardelli, K Pantel - Cancer cell, 2017 - cell.com
The inherent molecular heterogeneity of metastatic tumors and the ability of cancer
genomes to dynamically evolve are not properly captured by tissue specimens. Analysis of …

Tracking cancer progression: From circulating tumor cells to metastasis

F Castro-Giner, N Aceto - Genome medicine, 2020 - Springer
The analysis of circulating tumor cells (CTCs) is an outstanding tool to provide insights into
the biology of metastatic cancers, to monitor disease progression and with potential for use …

Single‐cell RNA sequencing in breast cancer: Understanding tumor heterogeneity and paving roads to individualized therapy

S Ding, X Chen, K Shen - Cancer Communications, 2020 - Wiley Online Library
Single‐cell RNA sequencing (scRNA‐seq) is a novel technology that allows transcriptomic
analyses of individual cells. During the past decade, scRNA‐seq sensitivity, accuracy, and …

Efficacy of circulating tumor cell count–driven vs clinician-driven first-line therapy choice in hormone receptor–positive, ERBB2-negative metastatic breast cancer: The …

FC Bidard, W Jacot, N Kiavue, S Dureau, A Kadi… - JAMA …, 2021 - jamanetwork.com
Importance The choice between chemotherapy and endocrine therapy as first-line treatment
for hormone receptor–positive, ERBB2 (also known as HER2)-negative metastatic breast …

Circulating tumor cells and circulating tumor DNA: challenges and opportunities on the path to clinical utility

M Ignatiadis, M Lee, SS Jeffrey - Clinical Cancer Research, 2015 - AACR
Recent technological advances have enabled the detection and detailed characterization of
circulating tumor cells (CTC) and circulating tumor DNA (ctDNA) in blood samples from …