Moderate‐to‐severe pain represents a heavy burden in patients' quality of life, and
ultimately in the society and in healthcare costs. The aim of this review was to summarize …

Introduction Tramadol is widely being used in chronic pain management for improving
patients' life quality and reducing trauma. Although it is listed in several medicinal …

Tramadol and tapentadol are extensively prescribed for the treatment of moderate to severe
pain. Although these drugs are very effective in pain treatment, the number of intoxications …

Tramadol abuse is one of the most frequent health problems in Egypt and worldwide. In
most cases, tramadol abused by men face a problem with premature ejaculation. Tramadol …

Tramadol and tapentadol, two structurally related synthetic opioid analgesics, are widely
prescribed due to the enhanced therapeutic profiles resulting from the synergistic …

Background Tramadol is a widely used synthetic opioid for moderate to severe pain. Some
studies have shown that tramadol can increase oxidative stress in different tissues of the …

Tramadol and tapentadol are fully synthetic and extensively used analgesic opioids,
presenting enhanced therapeutic and safety profiles as compared with their peers. However …

Tramadol and tapentadol are two atypical synthetic opioid analgesics, with monoamine
reuptake inhibition properties. Mainly aimed at the treatment of moderate to severe pain …

Tramadol, a broadly used opioid in recent years, is an effective analgesic agent for the
treatment of moderately severe acute or chronic pain. The liver and kidneys are responsible …

Aim: The present study aimed to elucidate the effects of tramadol on the testicular functions
of adult male rats due to the chronic usage of tramadol and the effect of its withdrawal …