Human gut-microbiome explorations have enriched our understanding of microbial
colonization, maturation, and dysbiosis in health-and-disease subsets. The enormous …

Alcohol-associated liver disease (ALD) comprises a spectrum of liver diseases that include:
steatosis to alcohol-associated hepatitis, cirrhosis, and ultimately hepatocellular carcinoma …

Background Associations between abnormal gut microbiome compositions and anxiety-like
behaviors are well established. However, it is unknown whether the gut microbiome …

Objective Frailty is a common geriatric syndrome that is diagnosed and staged based mainly
on symptoms. We aimed to evaluate frailty-related alterations of the intestinal permeability …

To understand the dynamic interplay between the human microbiome and host during
health and disease, we analyzed the microbial composition, temporal dynamics, and …

Substance use disorders (SUDs) represent a significant public health crisis. Worldwide,
5.4% of the global disease burden is attributed to SUDs and alcohol use, and many more …

Excessive alcohol intake is a leading cause of morbidity and mortality worldwide.
Perspective of alcohol-associated disease development is shifting, from the traditional …

Alcohol abuse is the seventh leading risk factor for death and disability-adjusted lifeyears
globally and the first cause of death among people between 15 to 49 years of age. 1 …

Introduction Increasing attention is being afforded to understanding the bidirectional
relationships that exist between oral medications and the gut microbiota, in an attempt to …

The gut microbiome modulates neurochemical function and behavior and has been
implicated in numerous central nervous system (CNS) diseases, including developmental …